ETHYL 5-OXOOCTANOATE

Base Information

• Chemical Name: ETHYL 5-OXOOCTANOATE
• CAS No.: 5205-40-3
• Molecular Formula: C10H18O3
• Molecular Weight: 186.24800
• Hs Code.: 2918300090
• Mol file: 5205-40-3.mol

Synonyms:5-Oxo-octansaeure-ethylester;5-Oxo-octansaeure-aethylester;5-oxo-octanoic acid ethyl ester;

Chemical Property of ETHYL 5-OXOOCTANOATE

Chemical Property:

• Vapor Pressure: 0.0126mmHg at 25°C
• Boiling Point: 260oC at 760 mmHg
• Flash Point: 107.7oC
• PSA: 43.37000
• Density: 0.959g/cm3
• LogP: 2.08900

Purity/Quality:

99% ^*data from raw suppliers

Ethyl5-oxooctanoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 5-OXOOCTANOATE

There total 6 articles about ETHYL 5-OXOOCTANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl glutaroyl chloride (5205-39-0) + n-propylmagnesium bromide (927-77-5) → 5-Oxo-octansaeure-ethylester (5205-40-3)

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ja510990v

Reference yield:

2-(1-oxo-butyl)-glutaric acid diethyl ester (858795-64-9) → 5-Oxo-octansaeure-ethylester (5205-40-3)

Guidance literature:

Multi-step reaction with 2 steps

1: diluted KOH

2: H₂SO₄

With potassium hydroxide; sulfuric acid;

DOI:10.1038/sj.bjp.0703324

Reference yield:

ethyl butyroyl acetate (3249-68-1) → 5-Oxo-octansaeure-ethylester (5205-40-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium ethylate / Zuletzt bei Siedetemperatur

2: diluted KOH

3: H₂SO₄

With potassium hydroxide; sulfuric acid; sodium ethanolate;

DOI:10.1038/sj.bjp.0703324

upstream raw materials:

ethanol

5-oxo-octanoic acid

2-(2-cyano-ethyl)-3-oxo-hexanoic acid ethyl ester

ethyl glutaroyl chloride

Refernces