Propyl palmitate

Base Information

• Chemical Name: Propyl palmitate
• CAS No.: 2239-78-3
• Molecular Formula: C19H38O2
• Molecular Weight: 298.51
• Hs Code.: 2915709000
• European Community (EC) Number: 218-803-1
• DSSTox Substance ID: DTXSID5073955
• Nikkaji Number: J184.205F
• Wikidata: Q63392073
• Mol file: 2239-78-3.mol

Synonyms:Propyl palmitate;Propyl hexadecanoate;2239-78-3;Hexadecanoic acid, propyl ester;PALMITIC ACID PROPYL ESTER;EINECS 218-803-1;AI3-31575;Propyl palmitate #;Palmitic acid, propyl ester;hexadecanoic acid propyl ester;SCHEMBL424533;DTXSID5073955;FT-0634158;Q63392073

Chemical Property of Propyl palmitate

Chemical Property:

• Vapor Pressure: 4.94E-05mmHg at 25°C
• Melting Point: 20.4°C
• Refractive Index: 1.444
• Boiling Point: 348.7 °C at 760 mmHg
• Flash Point: 167.6 °C
• PSA: 26.30000
• Density: 0.864 g/cm³
• LogP: 6.42090
• XLogP3: 8.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 17
• Exact Mass: 298.287180451
• Heavy Atom Count: 21
• Complexity: 214

Purity/Quality:

99%, ^*data from raw suppliers

PALMITIC ACID PROPYL ESTER 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OCCC
• Use Description: Palmitic acid propyl ester, also known as propyl palmitate, is a chemical compound with diverse applications across various fields. In the cosmetics and skincare industry, it serves as a common ingredient in cosmetic formulations, including creams, lotions, and ointments, due to its emollient properties. Propyl palmitate acts as a skin-conditioning agent, helping to moisturize and soften the skin, making it an essential component in skincare products. In the field of food and flavor science, it can be used as a food additive or flavoring agent, contributing to the taste and texture of certain food products. Additionally, in the pharmaceutical and drug formulation industry, it may find use as an excipient or carrier in medication formulations. Its multifunctionality as an emollient, food additive, and pharmaceutical excipient underscores its significance in cosmetics, food science, and pharmaceuticals, playing crucial roles in enhancing the quality of products in these diverse fields.

Technology Process of Propyl palmitate

There total 10 articles about Propyl palmitate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

propan-1-ol (71-23-8) + 1-hexadecylcarboxylic acid (57-10-3) → propyl palmitate (2239-78-3)

Guidance literature:

With alumina methanesulfonic acid; at 120 ℃; for 0.333333h; Microwave irradiation;

DOI:10.1080/00397911.2013.875210

Reference yield: 95.0%

propan-1-ol (71-23-8) + glyceroltripalmitate (555-44-2) → propyl palmitate (2239-78-3) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0)

Guidance literature:

With lithium perchlorate; 1) electrolyzis; 2) reflux, 7h;

DOI:10.1246/bcsj.58.1347

Reference yield: 95.0%

propan-1-ol (71-23-8) + hexadecanoic acid methyl ester (112-39-0) → propyl palmitate (2239-78-3)

Guidance literature:

With chloro-trimethyl-silane; at 25 ℃; for 6h;

DOI:10.1080/00397919908086082

upstream raw materials:

silver palmitate

1-iodo-propane

propan-1-ol

n-hexadecanoyl chloride

Refernces

• 1、 Fabian, Lucas,Gomez, Matias,Kuran, Juan A. Caturelli,Moltrasio, Graciela,Moglioni, Albertina. "Efficient microwave-assisted esterification reaction employing methanesulfonic acid supported on alumina as catalyst". . p. 2386 - 2392. Retrieved 2014/07/22.
• 2、 Romero, Cintia M.,Pera, Licia M.,Loto, Flavia,Baigori, Mario D.. "Specific enzyme-catalyzed hydrolysis and synthesis in aqueous and organic medium using biocatalysts with lipase activity from Aspergillus niger MYA 135". . p. 1361 - 1368. Retrieved 2013/01/15.