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Morphine, O(sup6)-methyl-

Base Information Edit
  • Chemical Name:Morphine, O(sup6)-methyl-
  • CAS No.:639-47-4
  • Molecular Formula:C18H21 N O3
  • Molecular Weight:299.37
  • Hs Code.:
  • NSC Number:134601
  • Mol file:639-47-4.mol
Morphine, O(sup6)-methyl-

Synonyms:Morphine, O6-methyl-;Morphine, O(sup6)-methyl-;NSC-134601;6-METHYL-MORPHINE ETHER;BDBM86950;NSC134601;CAS_5462505;NSC_5462505;Morphinan-3-ol,8-didehydro-4,5-.alpha.-epoxy-6.alpha.-methoxy-17-methyl-;WLN: T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FO1 JQ P1;Morphinan-3-ol,8-didehydro-4,5-epoxy-6-methoxy-17-methyl-, (5.alpha.,6.alpha.)-

Suppliers and Price of Morphine, O(sup6)-methyl-
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 33 raw suppliers
Chemical Property of Morphine, O(sup6)-methyl- Edit
Chemical Property:
  • Boiling Point:448.9°Cat760mmHg 
  • Flash Point:225.3°C 
  • PSA:41.93000 
  • Density:1.34g/cm3 
  • LogP:1.79010 
  • XLogP3:1.3
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:1
  • Exact Mass:299.15214353
  • Heavy Atom Count:22
  • Complexity:509
Purity/Quality:

97% *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)OC
Technology Process of Morphine, O(sup6)-methyl-

There total 2 articles about Morphine, O(sup6)-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
MORPHIN; With potassium hydride; In tetrahydrofuran; at 20 ℃; for 16.5h; Inert atmosphere;
methyl iodide; In tetrahydrofuran; for 4.25h; Inert atmosphere;
DOI:10.1093/nar/gkw1097
Guidance literature:
With sodium hydroxide; In methanol; for 8h; Heating;
DOI:10.1021/jm701457j
Guidance literature:
Multi-step reaction with 3 steps
1: Py / 2.5 h / Ambient temperature
2: MnO2 / tetrahydrofuran
3: aq. NaOH / methanol
With pyridine; manganese(IV) oxide; sodium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1021/jm00245a006
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