Benzoic acid, 2-amino-5-chloro-, 2-(imino-2-pyridinylmethyl)hydrazide

Base Information

• Chemical Name: Benzoic acid, 2-amino-5-chloro-, 2-(imino-2-pyridinylmethyl)hydrazide
• CAS No.: 104615-58-9
• Molecular Formula: C13H12ClN5O
• Molecular Weight: 289.724
• Mol file: 104615-58-9.mol

Synonyms:

Chemical Property of Benzoic acid, 2-amino-5-chloro-, 2-(imino-2-pyridinylmethyl)hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 2-amino-5-chloro-, 2-(imino-2-pyridinylmethyl)hydrazide

There total 2 articles about Benzoic acid, 2-amino-5-chloro-, 2-(imino-2-pyridinylmethyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

5-Chloroisatoic anhydride (4743-17-3) + picolinamidrazone (1005-02-3) → N-(2-amino-5-chlorobenzoyl)-2-pyrimidylamidrazone (104615-58-9)

Guidance literature:

In pyridine; Ambient temperature;

DOI:10.1021/jm00105a044

Reference yield:

2-Cyanopyridine (100-70-9,1232006-36-8) + 5-chloroanthranilic acid hydrazide (5584-15-6) → C13H12ClN5O (104615-58-9)

Guidance literature:

With sodium methylate; In methanol;

DOI:10.1007/s11172-012-0014-9

Reference yield: 91.0%

N-(2-amino-5-chlorobenzoyl)-2-pyrimidylamidrazone (104615-58-9) → 3-(2-amino-5-chlorophenyl)-5-(2-pyridyl)-2H-1,2,4-triazole (104615-57-8)

Guidance literature:

In diphenylether; biphenyl; at 180 ℃; for 3h;

DOI:10.1021/jm00105a044

upstream raw materials:

5-Chloroisatoic anhydride

picolinamidrazone

2-Cyanopyridine

5-chloroanthranilic acid hydrazide

Downstream raw materials:

3-(2-amino-5-chlorophenyl)-5-(2-pyridyl)-2H-1,2,4-triazole

2-(9-chloro-2-pyridin-2-yl-5,6-dihydro[1,5-c]quinazolin-5-yl)phenol

Refernces

• 1、 Francis, John E.,Cash, William D.,Barbaz, Beverly S.,Bernard, Patrick S.,Lovell, Richard A.,et al.. "Synthesis and Benzodiazepine Binding Activity of a Series of Novel Triazoloquinazolin-5(6H)-ones". . p. 281 - 290. Retrieved 2007/10/02.