4,4'-Dithiobisbenzoic Acid, Technical Grade

Base Information

• Chemical Name: 4,4'-Dithiobisbenzoic Acid, Technical Grade
• CAS No.: 1155-51-7
• Molecular Formula: C14H10O4S2
• Molecular Weight: 306.363
• Hs Code.: 2930909090
• Mol file: 1155-51-7.mol

Synonyms:Benzoicacid, 4,4'-dithiodi- (6CI,7CI,8CI);4,4'-Dithiobenzoic acid;4,4'-Dithiobis[benzoic acid];4,4'-Dithiodibenzoic acid;Bis(4-carboxyphenyl)disulfide;Bis(p-carboxyphenyl) disulfide;NSC 210281;p,p'-Dithiodi(benzoicacid);

Chemical Property of 4,4'-Dithiobisbenzoic Acid, Technical Grade

Chemical Property:

• Appearance/Colour: Pale Yellow Crystalline Powder
• Melting Point: 317-320 °C
• Boiling Point: 525.2 °C at 760 mmHg
• PKA: 3.58±0.10(Predicted)
• Flash Point: 271.4 °C
• PSA: 125.20000
• Density: 1.53 g/cm³
• LogP: 3.88240
• Storage Temp.: -20°C Freezer

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4''-DithiobisbenzoicAcid,TechnicalGrade ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4,4''-Dithiobisbenzoic Acid, Technical Grade (cas# 1155-51-7) is a compound useful in organic synthesis.

Technology Process of 4,4'-Dithiobisbenzoic Acid, Technical Grade

There total 22 articles about 4,4'-Dithiobisbenzoic Acid, Technical Grade which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

4-mercaptobenzoic acid (1074-36-8) → 4,4'-Dithiobisbenzoic acid (1155-51-7)

Guidance literature:

4-mercaptobenzoic acid; With dihydrogen peroxide; triethylamine; In methanol; water; at 5 - 25 ℃; for 0.666667h;

With hydrogenchloride; In methanol; water; at 5 - 25 ℃; for 1h;

Reference yield: 87.0%

2,4-diamino-5-methyl-furo[2,3-d]pyrimidine (67194-84-7) + 4-mercaptobenzoic acid (1074-36-8) → 4-[(2,4-diamino-5-methylfuro[2,3-d]pyrimidin-6-yl)thio]benzoic acid (1217309-62-0) + 4,4'-Dithiobisbenzoic acid (1155-51-7)

Guidance literature:

With iodine; In ethanol; water; for 3h; Reflux;

DOI:10.1016/j.bmc.2009.11.029

Reference yield: 79.3%

methoxyhydroquinone (824-46-4) + 4-mercaptobenzoic acid (1074-36-8) → 4,4'-Dithiobisbenzoic acid (1155-51-7) + 4-(4-methoxy-3,6-dioxocyclohexa-1,4-dien-1-yl)sulfanyl benzoic acid

Guidance literature:

With Myceliophthora thermophila laccase; In aq. phosphate buffer; at 20 ℃; for 0.333333h; pH=7; Reagent/catalyst; Green chemistry; Enzymatic reaction;

DOI:10.1016/j.molcatb.2015.12.012

upstream raw materials:

4-benzenediazonium-carboxylate

4-mercaptobenzoic acid

potassium thiophenolate

methylammonium carbonate

Downstream raw materials:

4-(2-Chloroethylsulfonyl)-benzoic acid

4-(Vinylsulfonyl)benzoesaeure

4-Vinylsulfonyl-benzoesaeure-ethylester

p-Carbethoxyphenyl-β-chlorethylsulfon

Refernces

• 1、 Carbonnel, Elodie,Besset, Tatiana,Poisson, Thomas,Labar, Daniel,Pannecoucke, Xavier,Jubault, Philippe. "18F-Fluoroform: A 18F-trifluoromethylating agent for the synthesis of SCF218F-aromatic derivatives". . p. 5706 - 5709. Retrieved 2017.
• 2、 Pazos, Elena,Garcia-Algar, Manuel,Penas, Cristina,Nazarenus, Moritz,Torruella, Arnau,Pazos-Perez, Nicolas,Guerrini, Luca,Vázquez, M. Eugenio,Garcia-Rico, Eduardo,Mascare?as, José L.,Alvarez-Puebla, Ramon A.. "Surface-Enhanced Raman Scattering Surface Selection Rules for the Proteomic Liquid Biopsy in Real Samples: Efficient Detection of the Oncoprotein c-MYC". . p. 14206 - 14209. Retrieved 2016.
• 3、 Veselska, Oleksandra,Cai, Liwen,Podbev?ek, Darjan,Ledoux, Gilles,Guillou, Nathalie,Pilet, Guillaume,Fateeva, Alexandra,Demessence, Aude. "Structural Diversity of Coordination Polymers Based on a Heterotopic Ligand: Cu(II)-Carboxylate vs Cu(I)-Thiolate". . p. 2736 - 2743. Retrieved 2018.
• 4、 Wei, Xiangxu,Zhong, Miao,Wang, Song,Li, Lexun,Song, Zi-Long,Zhang, Junmin,Xu, Jianqiang,Fang, Jianguo. "Synthesis and biological evaluation of disulfides as anticancer agents with thioredoxin inhibition". . . Retrieved 2021/03/24.
• 5、 Chang, Yalin,Li, Huiyi,Tao, Chaofu,Wang, Aiping,Wei, Yongge,Xie, Ya,Yu, Han,Yu, Shunming. "Transformation of arylboronic acids with sodium thiosulfate into organodisulfides catalyzed by a recyclable polyoxometalate-based Cr(iii) catalyst". supporting information. p. 6059 - 6064. Retrieved 2021/08/23.