2-Phenoxyethyl chloroacetate

Base Information

• Chemical Name: 2-Phenoxyethyl chloroacetate
• CAS No.: 103-57-1
• Molecular Formula: C10H11 Cl O3
• Molecular Weight: 214.6455
• NSC Number: 22577
• DSSTox Substance ID: DTXSID10281707
• Nikkaji Number: J2.061.202I
• Wikidata: Q82015755
• Mol file: 103-57-1.mol

Synonyms:2-Phenoxyethyl chloroacetate;103-57-1;2-phenoxyethylchloroacetate;SCHEMBL5908173;DTXSID10281707;NSC22577;NSC-22577

Chemical Property of 2-Phenoxyethyl chloroacetate

Chemical Property:

• Vapor Pressure: 0.00198mmHg at 25°C
• Boiling Point: 291.2°Cat760mmHg
• Flash Point: 119.3°C
• Density: 1.207g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 214.0396719
• Heavy Atom Count: 14
• Complexity: 167

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OCCOC(=O)CCl

Technology Process of 2-Phenoxyethyl chloroacetate

There total 3 articles about 2-Phenoxyethyl chloroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-Phenoxyethanol (122-99-6,56257-90-0,9004-78-8) + chloroacetyl chloride (79-04-9) → 2-phenoxyethyl chloroacetate (103-57-1)

Guidance literature:

With pyridine; In dichloromethane;

Reference yield:

2-Phenoxyethanol (122-99-6,56257-90-0,9004-78-8) → 2-phenoxyethyl chloroacetate (103-57-1)

Guidance literature:

With chloroacetic acid;

Reference yield:

→ 2-phenoxyethyl chloroacetate (103-57-1)

Guidance literature:

β-Hydroxyphenetol, ClCH2COOH, wenig HClO4, 2-stdg. Erwaermen in Bzl. bei 85-90grad;

upstream raw materials:

2-Phenoxyethanol

chloroacetyl chloride

Downstream raw materials:

(1,1,3-Trioxo-1,3-dihydro-1λ⁶-benzo[d]isothiazol-2-yl)-acetic acid 2-phenoxy-ethyl ester

Cyanessigsaeure-β-phenoxyethyl-ester

Refernces

• 1、 Svoboda, Jiri,Palecek, Jaroslav,Dedek, Vaclav. "PHASE TRANSFER CATALYSED N-SUBSTITUTION OF 2H-1,2-BENZISOTHIAZOLIN-3-ONE 1,1-DIOXIDE". . p. 1304 - 1310. Retrieved 2007/10/02.