5-bromo-2-nitro-N-phenyl-aniline

Base Information

• Chemical Name: 5-bromo-2-nitro-N-phenyl-aniline
• CAS No.: 6311-47-3
• Molecular Formula: C12H9BrN2O2
• Molecular Weight: 293.12
• Hs Code.: 2921440000
• Mol file: 6311-47-3.mol

Synonyms:N-(5-Bromo-2-nitrophenyl)-N-phenylamine;NSC 43212;5-Bromo-2-nitro-N-phenylaniline;

Chemical Property of 5-bromo-2-nitro-N-phenyl-aniline

Chemical Property:

• Vapor Pressure: 4.66E-06mmHg at 25°C
• Refractive Index: 1.686
• Boiling Point: 382.6 °C at 760 mmHg
• Flash Point: 185.2 °C
• PSA: 57.85000
• Density: 1.597 g/cm³
• LogP: 4.69710
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-2-nitro-N-phenylaniline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-bromo-2-nitro-N-phenyl-aniline

There total 4 articles about 5-bromo-2-nitro-N-phenyl-aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-bromo-2-fluoronitrobenzene (321-23-3) + aniline (62-53-3) → N-(5-bromo-2-nitrophenyl)benzenamine (6311-47-3)

Guidance literature:

In 1-methyl-pyrrolidin-2-one; at 110 ℃;

Reference yield: 70.0%

→ N-(5-bromo-2-nitrophenyl)benzenamine (6311-47-3)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide; at 80 ℃; for 22h; Inert atmosphere;

Reference yield:

2,4-dibromonitrobenzene (51686-78-3) + aniline (62-53-3) → N-(5-bromo-2-nitrophenyl)benzenamine (6311-47-3)

Guidance literature:

With sodium carbonate; In ethanol; at 20 ℃; for 18h;

DOI:10.1016/j.bmcl.2007.10.106

upstream raw materials:

4-bromo-1,2-dinitrobenzene

aniline

2,4-dibromonitrobenzene

4-bromo-2-fluoronitrobenzene

Downstream raw materials:

C₂₀H₁₄N₂O₂

1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(1-phenyl-1H-benzo[d]imidazol-6-yl)phenoxy)propan-2-ol

Refernces

• 1、 -. "KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE". Paragraph 0170; 0315; 0319. . Retrieved 2020/07/21.
• 2、 -. "Bipolar material and organic light emitting diode element". Paragraph 0032. . Retrieved 2019/04/14.