Technology Process of Eriocalyxin B
There total 6 articles about Eriocalyxin B which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: selenium(IV) oxide; tert.-butylhydroperoxide / dichloromethane / 24 h
2: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h
3: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / tetrahydrofuran; dimethyl sulfoxide / 0 - 20 °C
4: Jones reagent / water; acetone / 0.25 h / 0 °C
5: sodium iodide / acetonitrile / 12 h / 0 - 20 °C
6: palladium diacetate / acetonitrile / 6 h / 20 °C
With
tert.-butylhydroperoxide; selenium(IV) oxide; lithium aluminium tetrahydride; Jones reagent; palladium diacetate; sodium iodide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; acetone; acetonitrile;
4: |Jones Oxidation / 6: |Saegusa Oxidation;
DOI:10.1038/s41467-018-03546-9
- Guidance literature:
-
Multi-step reaction with 5 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h
2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / tetrahydrofuran; dimethyl sulfoxide / 0 - 20 °C
3: Jones reagent / water; acetone / 0.25 h / 0 °C
4: sodium iodide / acetonitrile / 12 h / 0 - 20 °C
5: palladium diacetate / acetonitrile / 6 h / 20 °C
With
lithium aluminium tetrahydride; Jones reagent; palladium diacetate; sodium iodide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; water; dimethyl sulfoxide; acetone; acetonitrile;
3: |Jones Oxidation / 5: |Saegusa Oxidation;
DOI:10.1038/s41467-018-03546-9