Carboxymethylazanium;chloride

Base Information

• Chemical Name: Carboxymethylazanium;chloride
• CAS No.: 6000-43-7
• Molecular Formula: C2H6ClNO2
• Molecular Weight: 111.528
• Hs Code.: 29224999
• Mol file: 6000-43-7.mol

Synonyms:carboxymethylazanium;chloride;2-aminoacetic acid;hydron;1-carboxymethanaminium chloride

Chemical Property of Carboxymethylazanium;chloride

Chemical Property:

• Appearance/Colour: White crystalline powder
• Vapor Pressure: 1.43E-11mmHg at 25°C
• Melting Point: 176-180 °C(lit.)
• Refractive Index: 1.644
• Boiling Point: 240.9 °C at 760 mmHg
• Flash Point: 99.5 °C
• PSA: 63.32000
• Density: 1.27g/cm3
• LogP: 0.53200
• Storage Temp.: 2-8°C
• Sensitive.: Hygroscopic
• Water Solubility.: SLIGHTLY SOLUBLE
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 111.0087061
• Heavy Atom Count: 6
• Complexity: 42.9

Purity/Quality:

99% ^*data from raw suppliers

Glycine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 22
• Safety Statements: 24/25-44

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(=O)O)[NH3+].[Cl-]
• Uses: Glycine hydrochloride is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.Glycine Hydrochloride is commonly used in buffer solutions, in electrophoresis, and preparative chromatography.

Technology Process of Carboxymethylazanium;chloride

There total 20 articles about Carboxymethylazanium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methoxycarbonylamino acetic acid methyl ester (70288-73-2) → 2-aminoethanoic acid hydrochloride (6000-43-7)

Guidance literature:

With hydrogenchloride; formic acid; In water; at 125 ℃; for 24h;

Reference yield: 96.0%

(3R)-3-<(1S,5R)-3-benzyl-7-oxo-4-oxa-2,6-diazabicyclo<3.2.0>hept-2-en-6-yl>-3,4,4-trimethylthietan-2-one (74743-61-6) → phenylacetic acid (103-82-2) + 2-aminoethanoic acid hydrochloride (6000-43-7) + (2-RS)-2-amino-3-mercapto-2,3-dimethylbutanoic acid hydrochloride (88168-76-7)

Guidance literature:

With hydrogenchloride; for 15h; Heating;

Reference yield: 95.0%

Ethyl N-(trichloroacetyl)-2-aminoacetate (116963-47-4) → 2-aminoethanoic acid hydrochloride (6000-43-7)

Guidance literature:

With potassium hydroxide; In methanol; Ambient temperature;

DOI:10.1021/jo00031a052

upstream raw materials:

Hippuric Acid

methoxycarbonylamino acetic acid methyl ester

N-(Trichloroacetyl)glycine

ethyl 2-(2,2,2-trifluoroacetamido)acetate

Downstream raw materials:

glycine ethyl ester hydrochloride

bis(2-methylphenyl) sulfone

3-(2-Amino-acetyl)-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid cyclohexylamide

{4-[2-(4-Chloro-phenyl)-6-oxo-4-thioxo-6H-1-oxa-3b,5-diaza-cyclopenta[a]pentalen-5-yl]-3,3-dimethyl-butyrylamino}-acetic acid

Refernces

• 1、 Neville,Beckstead,Black,Dawson,Shurvell. "Vibrational and NMR spectroscopic study of aged flurazepam mono- and dihydrochloride salts for content identity". . p. 1274 - 1279. Retrieved 1994.
• 2、 Ma, Bomou,Zhang, Meng,He, Chunju,Sun, Junfen. "New binary ionic liquid system for the preparation of chitosan/cellulose composite fibers". . p. 347 - 351. Retrieved 2012.
• 3、 Zorin,Lenkova,Khachaturyan,Zorin. "Synthesis of 2-Aminocarboxylic Acids on the Basis of Metalated Lithium Acylates". . p. 1590 - 1594. Retrieved 2018/11/10.