2-Chloro-1-trityl-1H-imidazole

Base Information

• Chemical Name: 2-Chloro-1-trityl-1H-imidazole
• CAS No.: 67478-48-2
• Molecular Formula: C₂₂H₁₇ClN₂
• Molecular Weight: 344.843
• Hs Code.: 2933290090
• DSSTox Substance ID: DTXSID50378387
• Wikidata: Q72460601
• Mol file: 67478-48-2.mol

Synonyms:2-Chloro-1-trityl-1H-imidazole;67478-48-2;2-chloro-1-tritylimidazole;2-chloro-1-(triphenylmethyl)-1H-imidazole;DTXSID50378387;MFCD02179527;AKOS015850373;AB11317;AS-60382;CS-0132487;FT-0646465;D96074

Chemical Property of 2-Chloro-1-trityl-1H-imidazole

Chemical Property:

• Melting Point: 200-202℃
• Boiling Point: 528.5 °C at 760 mmHg
• Flash Point: 273.4 °C
• PSA: 17.82000
• Density: 1.13 g/cm³
• LogP: 5.37670
• Storage Temp.: 2-8°C
• Water Solubility.: Insoluble in water.
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 344.1080262
• Heavy Atom Count: 25
• Complexity: 363

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloro-1-trityl-1H-imidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)N4C=CN=C4Cl
• Uses: 2-Chloro-1-trityl-1H-imidazole is an imidazole derivative useful in reactions needing on imidazole group.

Technology Process of 2-Chloro-1-trityl-1H-imidazole

There total 1 articles about 2-Chloro-1-trityl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

N-tritylimidazole (15469-97-3) → 2-chloro-1-trityl-1H-imidazole (67478-48-2)

Guidance literature:

With n-butyllithium; p-toluenesulfonyl chloride; In tetrahydrofuran; at -70 ℃;

upstream raw materials:

N-tritylimidazole

Refernces

• 1、 Daninos, Sophie,Mourabit, Ali Al,Ahond, Alain,Zurita, Manuel Bedoya,Poupat, Christiane,Potier, Pierre. "Synthesis of 2-aminoimidazole marine metabolites: clathrodine and 3'-amino-1'--prop-2'-ene". . p. 590 - 599. Retrieved 2007/10/02.