Nordihydrocapsaicin

Base Information

• Chemical Name: Nordihydrocapsaicin
• CAS No.: 28789-35-7
• Molecular Formula: C17H27 N O3
• Molecular Weight: 293.406
• Hs Code.: 2939800000
• European Community (EC) Number: 683-159-4
• UNII: RF657P8DA8
• DSSTox Substance ID: DTXSID3042217
• Nikkaji Number: J711.598I
• Wikipedia: Nordihydrocapsaicin
• Wikidata: Q2286631
• Metabolomics Workbench ID: 47307
• Mol file: 28789-35-7.mol

Synonyms:nordihydrocapsaicin

Chemical Property of Nordihydrocapsaicin

Chemical Property:

• Vapor Pressure: 4.15E-10mmHg at 25°C
• Boiling Point: 487 °C at 760 mmHg
• PKA: 9.76±0.20(Predicted)
• Flash Point: 248.3 °C
• PSA: 58.56000
• Density: 1.036 g/cm³
• LogP: 4.01440
• Storage Temp.: 2-8°C
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 293.19909372
• Heavy Atom Count: 21
• Complexity: 294

Purity/Quality:

98% ^*data from raw suppliers

Nordihydrocapsaicin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC

Technology Process of Nordihydrocapsaicin

There total 16 articles about Nordihydrocapsaicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-N-(4-hydroxy-3-methoxybenzyl)-7-methyloct-5-enamide (112375-60-7) → Nordihydrocapsaicin (28789-35-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 4h; under 760 Torr;

DOI:10.1021/jo00240a024

Reference yield:

norcapsaicin (61229-08-1) → Nordihydrocapsaicin (28789-35-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 4h; under 760 Torr;

DOI:10.1021/jo00240a024

Reference yield:

Vanillylamin (1196-92-5) → Nordihydrocapsaicin (28789-35-7)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 72 h / Ambient temperature

2: H₂ / 10percent Pd/C / ethanol / 4 h / 760 Torr

With hydrogen; palladium on activated charcoal; In diethyl ether; ethanol;

DOI:10.1021/jo00240a024

upstream raw materials:

Vanillylamin

7-methyloctanoyl chloride

(Z)-N-(4-hydroxy-3-methoxybenzyl)-7-methyloct-5-enamide

norcapsaicin

Refernces

• 1、 Kaga, Harumi,Miura, Masakatsu,Orito, Kazuhiko. "A Short Route to Dihydrocapsaicinoids". . p. 864 - 866. Retrieved 2007/10/02.