Technology Process of 1H-Indole, 3-iodo-1-[(4-methylphenyl)sulfonyl]-
There total 15 articles about 1H-Indole, 3-iodo-1-[(4-methylphenyl)sulfonyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
indole;
With
potassium hydroxide;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.5h;
Inert atmosphere;
With
iodine;
In
N,N-dimethyl-formamide;
for 1h;
Inert atmosphere;
p-toluenesulfonyl chloride;
With
potassium hydroxide;
In
N,N-dimethyl-formamide;
Inert atmosphere;
DOI:10.1021/acs.orglett.9b02687
- Guidance literature:
-
With
potassium phosphate; iodine;
In
acetonitrile;
at 100 ℃;
for 6h;
chemoselective reaction;
Glovebox;
Inert atmosphere;
DOI:10.1021/jacs.7b05155
- Guidance literature:
-
With
sodium hydroxide;
In
benzene;
at 25 ℃;
for 2h;
DOI:10.1021/ol7018086