3,3-Dimethylcyclobutanecarbonitrile

Base Information

• Chemical Name: 3,3-Dimethylcyclobutanecarbonitrile
• CAS No.: 53783-86-1
• Molecular Formula: C7H11N
• Molecular Weight: 109.1689
• Hs Code.: 2926909090
• Mol file: 53783-86-1.mol

Synonyms:Dimethyl-3,3-cyclobutane-carbonitrile;3,3-Dimethyl-cyclobutan-1-carbonitril;3,3-Dimethylcyclobutanecarbonitrile;Cyclobutanecarbonitrile,3,3-dimethyl;Cyclobutanecarbonitrile, 3,3-dimethyl-;3,3-Dimethyl-cyclobutancarbonitril;

Chemical Property of 3,3-Dimethylcyclobutanecarbonitrile

Chemical Property:

• Vapor Pressure: 1.79mmHg at 25°C
• Boiling Point: 166.4°Cat760mmHg
• Flash Point: 50°C
• PSA: 23.79000
• Density: 0.9g/cm³
• LogP: 1.94618

Purity/Quality:

3,3-Dimethylcyclobutanecarbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3-Dimethylcyclobutanecarbonitrile

There total 5 articles about 3,3-Dimethylcyclobutanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-Dimethyl-cyclobut-1-en-1-carbonitril (37676-94-1) → 3,3-dimethylcyclobutane-1-carbonitrile (53783-86-1)

Guidance literature:

With hydrogen; palladium/alumina; In pentane;

DOI:10.1021/jo01027a009

Reference yield:

3,3-dimethyl-2-piperidin-1-yl-cyclobutanecarbonitrile (19251-72-0) → 3,3-dimethylcyclobutane-1-carbonitrile (53783-86-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) TsOMe, (ii) aq. KOH, EtOH

2: H₂ / Pd-Al₂O₃ / pentane

With hydrogen; palladium/alumina; In pentane;

DOI:10.1021/jo01027a009

Reference yield:

toluene-4-sulfonic acid-(4-cyano-2,2-dimethyl-butyl ester) (101115-48-4) → 3,3-dimethylcyclobutane-1-carbonitrile (53783-86-1)

Guidance literature:

With sodium amide;

upstream raw materials:

toluene-4-sulfonic acid-(4-cyano-2,2-dimethyl-butyl ester)

3,3-Dimethyl-cyclobut-1-en-1-carbonitril

4,4-dimethyl-5-hydroxyvaleronitrile

4,4-dimethyl-5-oxopentanenitrile