1-Aminopyridinium iodide

Base Information

• Chemical Name: 1-Aminopyridinium iodide
• CAS No.: 6295-87-0
• Molecular Formula: C5H7N2^.I
• Molecular Weight: 222.028
• Hs Code.: 29333990
• European Community (EC) Number: 228-566-6
• NSC Number: 49542
• DSSTox Substance ID: DTXSID20978792
• Mol file: 6295-87-0.mol

Synonyms:1-Aminopyridinium iodide;6295-87-0;1-Aminopyridin-1-ium iodide;1-Amino-pyridinium;iodide;pyridin-1-ium-1-amine;Pyridinium, 1-amino-, iodide;aminopyridinium iodide;N-aminopyridinium iodide;MFCD00051893;1-Aminopyridiniumiodide;pyridin-1-ium-1-amine iodide;amino-pyridinium iodide;1-amino-pyridinium iodide;SCHEMBL376480;C5H7N2.I;1-Aminopyridinium iodide, 97%;DTXSID20978792;NDRLPYIMWROJBG-UHFFFAOYSA-M;C5-H7-N2.I;AMY39700;NSC49542;STR07438;NSC-49542;AKOS001016888;SB66371;s10071;SY009047;A0629;CS-0129676;FT-0636073;EN300-7176190;A834119;J-802020;W-203339;F2199-0089;lithium butyric acid hydroxide

Chemical Property of 1-Aminopyridinium iodide

Chemical Property:

• Appearance/Colour: pinkish crystalline powder
• Melting Point: 159-161 °C(lit.)
• PSA: 29.90000
• Density: 1.8200 (estimate)
• LogP: -2.72690
• Storage Temp.: 2-8°C
• Sensitive.: Light Sensitive
• Water Solubility.: Soluble in water (almost transparency).
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 221.96540
• Heavy Atom Count: 8
• Complexity: 48

Purity/Quality:

98%, ^*data from raw suppliers

1-Aminopyridinium iodide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=[N+](C=C1)N.[I-]
• Uses: 1-Aminopyridinium iodide is a reagent used as a building block to construct fused heterocycles, synthesis of substituted pyridines, dipolar cycloadditions, ylide type reactions.

Technology Process of 1-Aminopyridinium iodide

There total 5 articles about 1-Aminopyridinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

pyridine (110-86-1) → N-aminopyridin-1-ium iodide (6295-87-0)

Guidance literature:

With hydroxylamine-O-sulfonic acid; at 90 ℃; Cooling;

DOI:10.1002/pola.23832

Reference yield:

N-iminopyridinium ylide (25275-41-6) → N-aminopyridin-1-ium iodide (6295-87-0)

Guidance literature:

With hydrogen iodide; In ethanol;

DOI:10.1007/s13738-015-0700-2

Reference yield:

pyridine (110-86-1) → N-aminopyridin-1-ium iodide (6295-87-0)

Guidance literature:

With water; Behandeln der Reaktionsloesung mit wss. Jodwasserstoffsaeure bei -10grad bzw. -20grad;

upstream raw materials:

pyridine

water

N-iminopyridinium ylide

Downstream raw materials:

2-fluoro-3-(trifluoromethyl)pyrazolo<1,5-a>pyridine

2-methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester

2,3-bis(trifluoromethyl)pyrazolo<1,5-a>pyridine

pyridinium 1-[(phenyl)thiocarbonyl]aminide

Refernces

• 1、 Klinger, Daniel,Nilles, Katja,Theato, Patrick. "Synthesis of polymeric 1-iminopyridinium ylides as photoreactive polymers". experimental part. p. 832 - 844. Retrieved 2010/12/18.
• 2、 Sosnovsky, George,Purgstaller, Klaus. "Aminations with O-Diphenylphosphinylhydroxylamine. A Critical Evaluation". . p. 582 - 586. Retrieved 2007/10/02.