4'-Nitroacetophenonehydrazone

Base Information

• Chemical Name: 4'-Nitroacetophenonehydrazone
• CAS No.: 28153-22-2
• Molecular Formula: C8H9 N3 O2
• Molecular Weight: 179.178
• NSC Number: 11955
• Nikkaji Number: J1.744.135C
• Mol file: 28153-22-2.mol

Synonyms:4'-Nitroacetophenonehydrazone;SCHEMBL18862976;28153-22-2;NSC11955;NSC-11955;AKOS000506044

Chemical Property of 4'-Nitroacetophenonehydrazone

Chemical Property:

• Vapor Pressure: 9.82E-05mmHg at 25°C
• Boiling Point: 338.4°Cat760mmHg
• Flash Point: 158.5°C
• Density: 1.29g/cm³
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 179.069476538
• Heavy Atom Count: 13
• Complexity: 214

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NN)C1=CC=C(C=C1)[N+](=O)[O-]
• Isomeric SMILES: C/C(=N/N)/C1=CC=C(C=C1)[N+](=O)[O-]

Technology Process of 4'-Nitroacetophenonehydrazone

There total 4 articles about 4'-Nitroacetophenonehydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(4-nitrophenyl)ethanone (100-19-6) → 1-(4-nitrophenyl)ethanone hydrazone (28153-22-2)

Guidance literature:

With toluene-4-sulfonic acid; hydrazine hydrate; In ethanol; at 70 - 80 ℃;

DOI:10.1007/BF02494871

Reference yield:

(4-nitrophenyl)ethanone (100-19-6) → (E)-1-(1-(4-nitrophenyl)ethylidene)hydrazine (28153-22-2)

Guidance literature:

With hydrazine hydrate; In ethanol; at 100 - 120 ℃; for 0.0666667h; Microwave irradiation;

DOI:10.1007/s11094-019-02035-7

Reference yield:

p-Nitroacetophenone N,N-dimethylhydrazone (5757-82-4) → 1-(4-nitrophenyl)ethanone hydrazone (28153-22-2)

Guidance literature:

With hydrazine; In ethanol; Heating;

DOI:10.1021/jo01341a008

upstream raw materials:

p-Nitroacetophenone N,N-dimethylhydrazone

(4-nitrophenyl)ethanone

Downstream raw materials:

1,1-Dichloro-2-(4-nitrophenyl)-1-propene

1,2-bis(1-(4-nitrophenyl)ethylidene)hydrazine

(4-nitrophenyl)ethanone

3-methyl-6-nitro-1,2-diphenyl-1H-indene

Refernces

• 1、 -. "TRIPHENYLETHYLENE COMPOUNDS AND USES THEREOF". Paragraph 0147-0148. . Retrieved 2017/06/19.
• 2、 Nenajdenko, Valentine G.,Lenkova, Olesya N.,Shastin, Alexey V.,Balenkova, Elizabeth S.. "New synthetic approach to α-chlorocinnamates: First example of synthesis of functionally substituted alkenes using catalytic olefination reaction". . p. 573 - 577. Retrieved 2007/10/03.