ETHYL 2,4-DICHLOROPHENYL ACETATE

Base Information

• Chemical Name: ETHYL 2,4-DICHLOROPHENYL ACETATE
• CAS No.: 41022-54-2
• Molecular Formula: C10H10Cl2O2
• Molecular Weight: 233.094
• Hs Code.: 2916399090
• Mol file: 41022-54-2.mol

Synonyms:(2,4-Dichlorophenyl)aceticacid ethyl ester;Ethyl 2,4-dichlorophenylacetate;Ethyl2-(2,4-dichlorophenyl)acetate;NSC 33951;Butyric acid, 2,4-dichlorophenyl ester;Butanoic acid, 2,4-dichlorophenyl ester;2,4-dichlorophenyl butyrate;

Chemical Property of ETHYL 2,4-DICHLOROPHENYL ACETATE

Chemical Property:

• Boiling Point: 300.3 °C at 760 mmHg
• Flash Point: 121.8 °C
• PSA: 26.30000
• Density: 1.266 g/cm³
• LogP: 3.09900
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl 2,4-dichlorophenylacetate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of ETHYL 2,4-DICHLOROPHENYL ACETATE

There total 5 articles about ETHYL 2,4-DICHLOROPHENYL ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethanol (64-17-5) + 2,4-dichlorophenylacetic acid (19719-28-9) → ethyl 2-(2, 4-dichlorophenyl)acetate (41022-54-2)

Guidance literature:

With sulfuric acid; In benzene;

Reference yield: 66.0%

4-chloro-benzeneacetic acid, ethyl ester (14062-24-9) → ethyl 2-(2, 4-dichlorophenyl)acetate (41022-54-2)

Guidance literature:

With sodium persulfate; N-chloro-succinimide; trifluorormethanesulfonic acid; palladium diacetate; In 1,2-dichloro-ethane; at 70 ℃; for 7h; regioselective reaction; Sealed tube;

DOI:10.1002/anie.201300176

Reference yield: 25.0%

ethanol (64-17-5) + carbon monoxide (201230-82-2) + 2,4-dichlorobenzyl mercaptan (59293-67-3) → ethyl 2-(2, 4-dichlorophenyl)acetate (41022-54-2)

Guidance literature:

With dicobalt octacarbonyl; water; at 190 ℃; for 24h; under 43957.6 - 46543.3 Torr;

DOI:10.1021/jo00201a037

upstream raw materials:

ethanol

2,4-dichlorophenylacetic acid

ethyl α-bromo-2,4-dichlorophenylacetate

carbon monoxide

Downstream raw materials:

diethyl 2-(2,4-dichlorophenyl)-3-oxosuccinate

(2,4-dichlorophenyl)(4-nitrophenyl)methanone

2-(2,4-dichlorophenyl)propanoic acid

diethyl 2-(2,4-dichlorophenyl)propanedioate

Refernces

• 1、 Sun, Xiuyun,Shan, Gang,Sun, Yonghui,Rao, Yu. "Regio- and chemoselective C-H chlorination/bromination of electron-deficient arenes by weak coordination and study of relative directing-group abilities". supporting information. p. 4440 - 4444. Retrieved 2013/05/22.
• 2、 Mattiello, Leonardo,Luca, Carlo De,Rampazzo, Liliana. "Electrochemistry of some Ethyl α-Bromo(Dihalophenyl) Acetates and Electrochemical Synthesis of Diastereoisomeric Diethyl 2,3-Bis(dihalogenophenyl)Succinates". . p. 1041 - 1044. Retrieved 2007/10/02.