N,N-dipyridin-2-ylpyridin-2-amine

Base Information

• Chemical Name: N,N-dipyridin-2-ylpyridin-2-amine
• CAS No.: 10428-50-9
• Molecular Formula: C15H12 N4
• Molecular Weight: 248.287
• NSC Number: 176061
• DSSTox Substance ID: DTXSID70306400
• Nikkaji Number: J913.863C
• Wikidata: Q82053495
• Mol file: 10428-50-9.mol

Synonyms:N,N-dipyridin-2-ylpyridin-2-amine;10428-50-9;TRI(PYRIDIN-2-YL)AMINE;N,N-di(pyridin-2-yl)pyridin-2-amine;tri-2-pyridylamine;NSC176061;SCHEMBL2289138;DTXSID70306400;ADAL1063796;NSC-176061;N,N-BIS(PYRIDIN-2-YL)PYRIDIN-2-AMINE;F84528

Chemical Property of N,N-dipyridin-2-ylpyridin-2-amine

Chemical Property:

• Vapor Pressure: 1.67E-07mmHg at 25°C
• Boiling Point: 427.2°Cat760mmHg
• Flash Point: 212.2°C
• Density: 1.239g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 248.106196400
• Heavy Atom Count: 19
• Complexity: 228

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)N(C2=CC=CC=N2)C3=CC=CC=N3

Technology Process of N,N-dipyridin-2-ylpyridin-2-amine

There total 5 articles about N,N-dipyridin-2-ylpyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-bromo-pyridine (109-04-6) → tri-(2-pyridyl)amine (10428-50-9)

Guidance literature:

With potassium phosphate; copper(l) iodide; lithium amide; In N,N-dimethyl-formamide; at 130 ℃; for 24h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c2cc32252h

Reference yield: 54.0%

2-bromo-pyridine (109-04-6) + di(pyridin-2-yl)amine (1202-34-2) → tri-(2-pyridyl)amine (10428-50-9)

Guidance literature:

With copper(l) iodide; potassium phosphate monohydrate; In N,N-dimethyl-formamide; at 130 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2014.10.028

Reference yield: 20.0%

2-aminopyridine (504-29-0) + 2-bromo-pyridine (109-04-6) → tri-(2-pyridyl)amine (10428-50-9)

Guidance literature:

In ethanol; for 0.1h; microwave heating;

DOI:10.1016/0022-328X(89)85201-5

upstream raw materials:

2-aminopyridine

2-iodopyridine

di(pyridin-2-yl)amine

2-bromo-pyridine

Downstream raw materials:

C₂₁H₁₉MoN₄O₂⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-)

[ReO(OCH₂CH₂O)(PPh₃)(tri-2-pyridylamine)]Cl

[IrH2(PPh3)2(η(2)-tri-2-pyridylamine)]BF4

bis{tris(2-pyridyl)amine}ruthenium(II) tosylate

Refernces

• 1、 Ali, Mushtaq,Bond, Stephen P.,Mbogo, Shaaban A.,McWhinnie, William R.,Watts, Philip M.. "Use of a domestic microwave oven in organometallic chemistry". . p. 11 - 14. Retrieved 1989.