4-HYDROXY-B-NITROSTYRENE

Base Information

• Chemical Name: 4-HYDROXY-B-NITROSTYRENE
• CAS No.: 3179-08-6
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.148
• Hs Code.: 2908990000
• Mol file: 3179-08-6.mol

Synonyms:Phenol,p-(2-nitrovinyl)- (6CI,7CI,8CI);4-(2-Nitroethenyl)phenol;4-(2-Nitrovinyl)phenol;4-Hydroxy-b-nitrostyrene;4-Hydroxy-w-nitrostyrene;NSC 30299;NSC 81594;p-Hydroxy-b-nitrostyrene;

Chemical Property of 4-HYDROXY-B-NITROSTYRENE

Chemical Property:

• Melting Point: 167-171 °C(lit.)
• Boiling Point: 318.3 °C at 760 mmHg
• PKA: 8.04±0.13(Predicted)
• Flash Point: 144.2 °C
• PSA: 66.05000
• Density: 1.32 g/cm³
• LogP: 2.16280
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

4-(2-Nitrovinyl)phenol >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXY-B-NITROSTYRENE

There total 12 articles about 4-HYDROXY-B-NITROSTYRENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

nitromethane (75-52-5) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-(2-nitrovinyl)phenol (3179-08-6)

Guidance literature:

AP-E₁; at 90 ℃; for 0.25 - 0.266667h; Product distribution / selectivity;

Reference yield: 88.0%

para-coumaric acid (7400-08-0,50940-26-6) → 4-(2-nitrovinyl)phenol (3179-08-6)

Guidance literature:

With tert.-butylnitrite; silica gel; In acetonitrile; at 100 ℃; under 2250.23 Torr; Time; Temperature; Pressure; Microwave irradiation;

DOI:10.1080/00397911.2012.735331

Reference yield:

nitromethane (75-52-5) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-(2-nitrovinyl)phenol (3179-08-6) + 1-(4-hydroxyphenyl)-2-nitroethanol

Guidance literature:

With secondary amine functionalized carbon microspheres in toluene; at 90 ℃; for 0.5h;

upstream raw materials:

4-acetoxy-β-nitro-styrene

nitromethane

4-hydroxy-benzaldehyde

4-formylphenyl acetate

Downstream raw materials:

4-acetoxy-β-nitro-styrene

Carbamic acid 4-((E)-2-nitro-vinyl)-phenyl ester

2-(4-hydroxyphenyl)-1-nitroethane

Phosphoric acid diethyl ester 4-((E)-2-nitro-vinyl)-phenyl ester

Refernces

• 1、 -. "Synthesis of functionalized carbon microspheres and their catalyst activity in C—O and C—N bond formation reactions". Page/Page column 8-9. . Retrieved 2019/02/14.
• 2、 Sudhakar Chary,Rajanna,Krishnaiah,Srinivas. "Zeolite Y-assisted nitration of aromatic and heterocyclic compounds and decarboxylative nitration of α,β-unsaturated acids under non-conventional conditions". . p. 1430 - 1434. Retrieved 2016/03/08.