7-CARBOXY-1-HEPTANETHIOL

Base Information

• Chemical Name: 7-CARBOXY-1-HEPTANETHIOL
• CAS No.: 74328-61-3
• Molecular Formula: C8H16O2S
• Molecular Weight: 176.28
• Mol file: 74328-61-3.mol

Synonyms:8-Mercaptooctanoicacid;8-Thiooctanoic acid;

Chemical Property of 7-CARBOXY-1-HEPTANETHIOL

Chemical Property:

• Vapor Pressure: 0.000237mmHg at 25°C
• Refractive Index: n20/D 1.4808
• Boiling Point: 302 °C at 760 mmHg
• PKA: 4.77±0.10(Predicted)
• Flash Point: 136.4 °C
• PSA: 76.10000
• Density: 1.041 g/cm³
• LogP: 2.34140
• Storage Temp.: ?20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

8-Mercaptooctanoic acid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: MOA is a used as a SAM for surface modification of gold electrodes for quartz crystal microbalance (QCMB) measurement. It may be used as a monolayer that facilitates ferritin absorption on gold electrodes for uptake of excess iron in the cell. It may also be used for preparation of nitric oxide based gold nanoparticles (NO-AuNPs) for macrophage photo-thermal therapy under NIR irradiation.

Technology Process of 7-CARBOXY-1-HEPTANETHIOL

There total 2 articles about 7-CARBOXY-1-HEPTANETHIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

8-bromooctanoic acid (17696-11-6) → 8-mercapto-octanoic acid (74328-61-3)

Guidance literature:

With sodium hydroxide; sulfuric acid; thiourea; In water;

Reference yield:

→ 8-mercapto-octanoic acid (74328-61-3)

Guidance literature:

Reference yield:

8-mercapto-octanoic acid (74328-61-3) + 1,2-diamino-benzene (95-54-5) → N-(2-aminophenyl)-8-mercaptooctanamide

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 25 ℃; for 24h; Sonication;

upstream raw materials:

8-bromooctanoic acid

Downstream raw materials:

9-thiaheptadecanoic acid

9-thiaoctadecanoic acid

Refernces

• 1、 -. "Azole derivatives". . . Retrieved 2008/06/13.