NSC10978

Base Information

• Chemical Name: NSC10978
• CAS No.: 5411-50-7
• Molecular Formula: C6H3Br2NO2
• Molecular Weight: 280.903
• Hs Code.: 2904909090
• Mol file: 5411-50-7.mol

Synonyms:Benzene, 1,2-dibromo-4-nitro-;1,2-Dibromo-4-nitrobenzene;

Chemical Property of NSC10978

Chemical Property:

• Melting Point: 58.5°C
• Refractive Index: 1.6400 (estimate)
• Boiling Point: 296°C (rough estimate)
• PSA: 45.82000
• Density: 2.2414 (rough estimate)
• LogP: 3.64300
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1,2-Dibromo-4-nitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NSC10978

There total 15 articles about NSC10978 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,3-dibromobenzene (583-53-9) → 3,4-dibromonitrobenzene (5411-50-7)

Guidance literature:

With nitric acid; at 20 ℃;

DOI:10.1039/b417012a

Reference yield: 66.0%

→ 3,4-dibromonitrobenzene (5411-50-7)

Guidance literature:

With Bromotrichloromethane; trichloroisocyanuric acid; bromine; at 10 - 120 ℃; for 60h; Photolysis;

Reference yield: 58.0%

2-bromo 5-nitroaniline (10403-47-1) + allyl bromide (106-95-6) → 3,4-dibromonitrobenzene (5411-50-7) + allyl-2-bromo-5-nitrobenzene

Guidance literature:

With tert.-butylnitrite; In acetonitrile; at 42 - 45 ℃; for 1.33h;

DOI:10.1021/jo0258103

upstream raw materials:

2-bromo-4-nitroaniline

para-nitrophenyl bromide

2,3-dibromobenzene

2-bromo 5-nitroaniline

Downstream raw materials:

N,N'-bis-(2-bromo-4-nitro-phenyl)-ethylenediamine

1-nitro-3,4-bis(trimethylsilylethynyl)benzene

3,4-dibromoacetanilide

N-(4-heptylphenyl)acetamide

Refernces

• 1、 -. "PROCESS FOR THE PREPARATION OF ORGANIC HALIDES". Paragraph 00139. . Retrieved 2017/08/01.
• 2、 -. "Site-specific cleavage of nucleic acids by photoreactive conjugates". Page/Page column 3. . Retrieved 2012/08/28.