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Cas Database |
| Name |
Oxamethacin |
EINECS | N/A |
| CAS No. | 27035-30-9 | Density | 1.35g/cm3 |
| PSA | 80.56000 | LogP | 3.73900 |
| Solubility | N/A | Melting Point |
181-182° (dec) |
| Formula | C19H17 Cl N2 O4 | Boiling Point | °Cat760mmHg |
| Molecular Weight | 372.808 | Flash Point | °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion and intraperitoneal routes. An anti-inflammatory agent. When heated to decomposition it emits toxic fumes of Cl− and NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Indole-3-acetohydroxamicacid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- (8CI); Dinulcid; Flogar;Indoxamic acid; Oxametacin |
Article Data | 12 |
Oxamethacin Chemical Properties
IUPAC Name: 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-hydroxyacetamide
Synonyms of Oxamethacin (CAS NO.27035-30-9) : 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetohydroxamic acid ;1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl- (9CI) ; Indole-3-acetohydroxamic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- ; Oxametacin
InChI:InChI=1/C19H17ClN2O4/c1-11-15(10-18(23)21-25)16-9-14(26-2)7-8-17(16)22(11)19(24)12-3-5-13(20)6-4-12/h3-9,25H,10H2,1-2H3,(H,21,23)
CAS NO: 27035-30-9
Molecular Formula:C19H17ClN2O4
Molecular Weight :372.8023
Molecular Structure :.png)
EINECS: 248-179-6
Index of Refraction: 1.63
Surface Tension: 49.4 dyne/cm
Density: 1.35 g/cm3
Oxamethacin Uses
Oxamethacin (CAS NO.27035-30-9) is non-steroidal anti-inflammatory analgesic.
Oxamethacin Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 32mg/kg (32mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. | |
| mouse | LD50 | oral | 92mg/kg (92mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. | |
| rat | LD50 | intraperitoneal | 40mg/kg (40mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. | |
| rat | LD50 | oral | 78mg/kg (78mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. |
Oxamethacin Safety Profile
Poison by ingestion and intraperitoneal routes. An anti-inflammatory agent. When Oxamethacin (CAS NO.27035-30-9) is heated to decomposition, it emits toxic fumes of Cl− and NOx.
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