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Indeno[1,2,3-cd]pyrene

  • Name Indeno[1,2,3-cd]pyrene
  • EINECS205-893-2
  • CAS No. 193-39-5
  • Density1.379 g/cm3
  • PSA0.00000
  • LogP6.23140
  • SolubilityN/A
  • Melting Point163.6oC
  • FormulaC22H12
  • Boiling Point497.101 °C at 760 mmHg
  • Molecular Weight276.337
  • Flash Point247.24 °C
  • Transport InformationN/A
  • AppearanceYellow crystals
  • Safety45-53-62-61-60-36/37
  • Risk Codes45-46-51/53-60-61-67-65-50/53-38-11-39/23/24/25-23/24/25-40
  • Molecular Structure
    Molecular Structure of 193-39-5 (Indenopyrene)
  • Hazard SymbolsFlammableF,HarmfulXn,DangerousN,ToxicT
  • SynonymsFlammableF,HarmfulXn,DangerousN,ToxicT
  • Article Data34

Indeno[1,2,3-cd]pyrene Synthetic route

Trifluoro-methanesulfonic acid 2-pyren-1-yl-phenyl ester

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; bis-triphenylphosphine-palladium(II) chloride In N,N-dimethyl-formamide at 135 - 140℃; for 6h;91%
102662-21-5

2-(pyren-1-yl)aniline

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With tert.-butylnitrite In acetonitrile at 20℃; for 10h;85%
With sulfuric acid; acetic acid; sodium nitrite anschliessendes Erwaermen mit Kupfer-Pulver;

C22H15N

536-74-3

phenylacetylene

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With fac-tris(2-phenylpyridinato-N,C2')iridium(III); tert.-butylnitrite In acetonitrile at 20℃; for 15h; Sealed tube; Irradiation;84%
377737-93-4

1-bromo-2-(1-pyrenyl)benzene

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; bis-triphenylphosphine-palladium(II) chloride In N,N-dimethyl-formamide at 140℃; for 11h; Inert atmosphere;72%
1714-29-0

1-bromopyrene

244205-40-1

(2-bromophenyl)boronic acid

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; tricyclohexylphosphine; tris(dibenzylideneacetone)dipalladium (0) In N,N-dimethyl-formamide at 155℃; for 48h;51%
92681-17-9, 93861-97-3

endo-(8bSR,8cSR,12bRS,12aRS)-8b,8c,11,12,12a,12b-hexahydrobenzocyclobuta<1,2-e>pyrene

A

7267-88-1

4-phenylpyrene

B

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In chloroform Heating;A 10%
B 4%
7267-88-1

4-phenylpyrene

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With aluminium trichloride; sodium chloride at 120℃;
5695-26-1

indeno[1,2,3-cd]pyrene-11,12-dicarboxylic acid-anhydride

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
With soda lime
129-00-0

pyrene

71-43-2

benzene

193-39-5

Indeno[1,2,3-cd]pyrene

Conditions
ConditionsYield
at 750℃;
85-01-8

phenanthrene

A

129-00-0

pyrene

B

91-20-3

naphthalene

C

193-39-5

Indeno[1,2,3-cd]pyrene

D

120-12-7

anthracene

Conditions
ConditionsYield
at 850℃; Further byproducts given;

Indeno[1,2,3-cd]pyrene Chemical Properties

Product Name: Indeno(1,2,3-c,d)pyrene (193-39-5)


Molecular Formula: C22H12
Molecular Weight:276.33g/mol
Mol File: 193-39-5.mol
Einecs:205-893-2
Appearance: Crystalline Solid,Yellow crystal
Melting Point:150-153°C (dec)
Boiling point: 497.1 °C at 760 mmHg
storage Temperature:APPROX 4°C
Flash Point: 247.2 °C
Density: 1.378 g/cm3
Hazard Symbols: Confirmed carcinogen
Stability: Stable. Incompatible with strong oxidizing agents.
Product Categories: o-phenylenepyrene ; 1,10-(1,2-phenylene)pyrene ; 1,10-(o-phenylene)pyrene ; 1,10-(ortho-phenylene)pyrene ; 2,3-phenylenepyrene ; ideno(1,2,3-cd)pyrene ; indenopyrene ; indenopyrene(non-specificname).
Synonyms of Ethyl Indeno(1,2,3-c,d)pyrene (193-39-5) : semivolatiles ; e-lanalytical standards ; ichemical class ; alpha sort ; alphabetic ; analytical standards ; semivolatiles ; chemical class ; hydrocarbons ; neats.

Indeno[1,2,3-cd]pyrene Toxicity Data With Reference

1.    

mma-sat 3 µg/plate/48H

    FCTXAV    Food and Cosmetics Toxicology. 17 (1979),141.
2.    

otr-ham:lng 100 µg/L

    TXCYAC    Toxicology. 17 (1980),149.

Indeno[1,2,3-cd]pyrene Consensus Reports

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 32 , 1983,p. 373.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 3 , 1973,p. 229.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

Indeno[1,2,3-cd]pyrene Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes.
Analytical Methods:
For occupational chemical analysis use NIOSH: Polynuclear Aromatic Hydrocarbons (HPLC), 5506; (GC), 5515.Safety Information of Ethyl Indeno(1,2,3-c,d)pyrene (193-39-5):


Hazard Codes:  F,Xn,N,T
Risk Statements:  45-46-51/53-60-61-67-65-50/53-38-11-39/23/24/25-23/24/25-40
45:  May cause cancer
46:  May cause heritable genetic damage
51:  Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
60:  May impair fertility
61:  May cause harm to the unborn child
67:  Vapors may cause drowsiness and dizziness
65:  Harmful: May cause lung damage if swallowed
50:  Very Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
38:  Irritating to the skin
11:  Highly Flammable
39:  Danger of very serious irreversible effects
23:  Toxic by inhalation
24:  Toxic in contact with skin 
25:  Toxic if swallowed
40:  Limited evidence of a carcinogenic effect
Safety Statements:  45-53-62-61-60-36/37
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53:  Avoid exposure - obtain special instruction before use
61:  Avoid release to the environment. Refer to special instructions safety data sheet 
62:  If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label
60:  This material and/or its container must be disposed of as hazardous waste
36:  Wear suitable protective clothing 
37:  Wear suitable gloves 

Indeno[1,2,3-cd]pyrene Analytical Methods

For occupational chemical analysis use NIOSH: Polynuclear Aromatic Hydrocarbons (HPLC), 5506; (GC), 5515.

Indeno[1,2,3-cd]pyrene Specification

 Indeno(1,2,3-c,d)pyrene (193-39-5) is a yellow crystals from cyclohexane and bright-yellow plates from pet ether/C6H6. Mp: 161–163.5°.It's Chemical Properties is solid and insoluble in water.It has Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as INDENO(1,2,3-C,D)PYRENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenati(acidcatalyst),nitration,sulfonation, and the Friedel-Crafts reaction.

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