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Imipramine-N-oxide hydrochloride

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Name

Imipramine-N-oxide hydrochloride

EINECS N/A
CAS No. 19864-71-2 Density N/A
PSA 32.67000 LogP 4.77550
Solubility N/A Melting Point N/A
Formula C19H24 N2 O . Cl H Boiling Point N/A
Molecular Weight 332.91 Flash Point N/A
Transport Information N/A Appearance N/A
Safety A poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. Experimental reproductive effects. Used as an antidepressant. When heated to decomposition it emits very toxic fumes of HCl and NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 19864-71-2 (Imipraminoxide) Hazard Symbols N/A
Synonyms

5H-Dibenz[b,f]azepine,5-[3-(dimethylamino)propyl]-10,11-dihydro-, N-oxide, hydrochloride (7CI);5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, N-oxide,monohydrochloride (8CI); 5H-Dibenz[b,f]azepine-5-propanamine,10,11-dihydro-N,N-dimethyl-, N-oxide, monohydrochloride (9CI); Imipramine 5-oxidehydrochloride; Imipramine N-oxide hydrochloride; Imiprex

 

Imipramine-N-oxide hydrochloride Chemical Properties

Product Name: Imipramine-N-oxide hydrochloride
CAS Registry Number: 19864-71-2
IUPAC Name: N,N-dimethyl-3-(11-oxido-5,6-dihydrobenzo[b][1]benzazepin-11-ium-11-yl)propan-1-amine hydrochloride
Molecular Weight: 332.8676 [g/mol]
Molecular Formula: C19H25ClN2O
H-Bond Donor: 1
H-Bond Acceptor: 2 
Classification Code: Antidepressive ;Drug / Therapeutic Agent ;Reproductive Effect
Related Registry Number: 6829-98-7 (Parent)
Following is the molecular structure of Imipramine-N-oxide hydrochloride (CAS NO.19864-71-2) is:

Imipramine-N-oxide hydrochloride Uses

 Imipramine-N-oxide hydrochloride (CAS NO.19864-71-2)  can be used as an antidepressant.

Imipramine-N-oxide hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 150mg/kg (150mg/kg)   United States Patent Document. Vol. #3574852,
mouse LD50 intravenous 86mg/kg (86mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 601, 1976.
mouse LD50 oral 640mg/kg (640mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 601, 1976.
mouse LD50 subcutaneous 255mg/kg (255mg/kg) BEHAVIORAL: ATAXIA Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 601, 1976.
rat LD50 intraperitoneal 90mg/kg (90mg/kg)   United States Patent Document. Vol. #3574852,
rat LD50 oral 770mg/kg (770mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 601, 1976.
rat LD50 subcutaneous 260mg/kg (260mg/kg) BEHAVIORAL: ATAXIA Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 601, 1976.

Imipramine-N-oxide hydrochloride Safety Profile

A poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NOx
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

Imipramine-N-oxide hydrochloride Specification

 Imipramine-N-oxide hydrochloride , its cas register number is 19864-71-2. It also can be called Imipramine-N-oxide HCl
; Imiprex ; 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-, 5-oxide, monohydrochloride .

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