Beilstein Journal of Organic Chemistry p. 1503 - 1511 (2016)
Update date:2022-08-11
Topics:
Mallia, Carl J.
Walter, Gary C.
Baxendale, Ian R.
The flow synthesis of ortho-substituted carboxylic acids, using carbon monoxide gas, has been studied for a number of substrates. The optimised conditions make use of a simple catalyst system compromising of triphenylphosphine as the ligand and palladium acetate as the pre-catalyst. Carbon monoxide was introduced via a reverse "tube-in-tube" flow reactor at elevated pressures to give yields of carboxylated products that are much higher than those obtained under normal batch conditions.
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Doi:10.1021/cs400988w
(2014)Doi:10.1021/ja0390552
(2004)Doi:10.1021/ja00821a034
(1974)Doi:10.1080/00397919608003491
(1996)Doi:10.1016/j.ejmech.2016.12.047
(2017)Doi:10.14233/ajchem.2013.14164
(2013)