Journal of Organic Chemistry p. 10163 - 10176 (2015)
Update date:2022-08-23
Topics:
Nottingham, Chris
Benson, Robert
Müller-Bunz, Helge
Guiry, Patrick J.
The synthesis of a range of novel gem-disubstituted ferrocene-oxazoline ligands and their application in both the asymmetric ethyl- and phenylzinc additions to aldehydes is reported. These studies reveal that gem-disubstitution of i-Pr-containing ferrocene oxazoline ligands results in increased enantioselectivity compared to their unsubstituted counterparts. Utilizing zinc catalysis, these ligands provided a wide range of secondary alcohols in yields of up to 93% with ee's of up to >99%. An interesting crystal structure of a ferrocene oxide-lithium tetramer showing lithium-nitrogen coordination in the solid state is also presented.
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(1974)Doi:10.1039/c39950001549
(1995)Doi:10.1023/A:1015868201847
(2002)Doi:10.1007/s00044-013-0730-1
(2014)Doi:10.1177/0269881109354927
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