Mixing with microwaves: Solvent-free and catalyst-free synthesis of pyrazoles and diazepines

Article abstract of DOI:10.1016/j.tetlet.2013.01.029

A simple and facile condensation of hydrazines/hydrazides and diamines with 1,3-diketones/β-ketoester leads to the preparation of pyrazoles and diazepines in high yields. This eco-friendly protocol is accelerated by microwave heating and efficiently carried out without any reaction solvent or catalyst in as little as 5 min.