Journal of the Chemical Society. Perkin transactions II p. 1803 - 1808 (1984)
Update date:2022-08-11
Topics:
Al-Kaabi, Sharifa S.
Hallett, Geoffrey
Meyer, Thomas A.
Williams, D. Lyn H.
For both N-methyl-N-nitrosoaniline and N-nitrosodiphenylamine, the catalytic effect of halide ion, thiocyanate ion, and thiourea in the denitrosation reaction in acid solution disappears at high nucleophile concentrations.This suggests a change to an earlier rate-limiting step.The data, including the variation of rate constant with acidity, are quantitatively in accord with a reaction mechanism involving protonation of the nitosamine followed by nucleophilic attack, either stage being rate limiting, depending on the reactivity and concentration of the nucleophile.The kinetic solvent isotope effect kH2O/kD2O decreases from 1.59 at 0.43M-thiourea to 0.71 at 0.015M-thiourea, which is consistent with a change from general acid catalysis at high
Contact:15122693241
Address:Tianjin Huanyu Group import and export Inc ,NO.3 Yunnan Road,Tianjin,China
Shandong Wanda Organosilicon New Material Co., Ltd
Contact:+86-21-54177116;54302881
Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Contact:+86-531-58668191 58668193 58668196 58661173
Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province
Henan Tianfu Chemical Co., Ltd.
website:http://www.tianfuchem.com
Contact:86-371-55170693/55170694
Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China
Contact:0086-21-80264647
Address:RM 202, NO 1602 West Zhongshan Rd, Shanghai, China
Doi:10.1021/ja00134a005
(1995)Doi:10.1039/c5ra13291f
(2015)Doi:10.1007/s11030-018-9871-y
(2019)Doi:10.1021/ja00759a053
(1972)Doi:10.1021/ol0483551
(2004)Doi:10.1016/j.jssc.2012.03.012
(2012)