Journal of Organic Chemistry p. 8282 - 8289 (2017)
Update date:2022-08-05
Topics:
Lv, Yunhe
Pu, Weiya
Chen, Qian
Wang, Qingqing
Niu, Jiejie
Zhang, Qian
The copper-catalyzed highly regioselective aminodifluoroalkylation of alkynes and α-bromodifluoroacetamides was realized for the first time. With this method, 3,3-difluoro-1H-pyrrol-2(3H)-ones were constructed in a single step from various alkynes and α-b
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