Journal of Organometallic Chemistry p. 55 - 62 (1986)
Update date:2022-08-02
Topics:
Brunner, Henri
Knott, Alfons
Kunz, Manfred
Thalhammer, Elisabeth
The Z- and E-isomers of the α-N-benzoylamino-2-butenoic acid methyl ester, the E/Z mixtures of α-N-benzoylamino-2-butenoic acid, and the Z-form of α-N-acetylamino-2-butenoic acid were hydrogenated enantioselectively.The hydrogenation products are derivatives of α-aminobutyric acid, which can be reduced to aminobutanol, the optically active component of the antituberculosis drug (+)-ethambutol.In situ catalysts consisting of
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