Journal of Heterocyclic Chemistry p. 1469 - 1478 (1997)
Update date:2022-08-05
Topics:
Kato
Harada
Morie
An efficient asymmetric synthesis of (R)-6-amino-1-methyl-4-(3- methylbenzyl)hexahydro-1H-1,4-diazepine [(R)-2] which serves as the amine part of (R)-1, a potent and selective 5-HT3 receptor antagonist, is described. Formation of the hexahydro-
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Doi:10.1021/acs.joc.5b02670
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