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(b) Fenical, W.; Sims, J. J.; Squatrito, D.; Wing, R. M.; Radlick, P. Zonarol and
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undulata against the abalone Haliotis discus hannai. Nippon Suisan Gakkaishi
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2. (a) Rodriguez, J.; Quin˜oa, E.; Riguera, R.; Peters, B. M.; Abrell, L. M.; Crews, P.
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tylospongia elegans. Tetrahedron 1992, 48, 6667–6680; (b) Talpir, R.; Rudi, A.;
Kashman, Y.; Loya, Y.; Hizi, A. Three new sesquiterpene hydroquinones from
marine origin. Tetrahedron 1994, 50, 4179–4184; (c) Coval, S. J.;
Conover, M. A.; Mierzwa, R.; King, A.; Puar, M. S.; Phife, D. W.; Pai, J.-K.;
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Note that in these papers the optical rotation of ent-chromazonarol ent-1 was
not reported; only the optical rotation of phenolic monoactate of ent-1 is
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4. Fenical, W.; McConnell, O. Chromazonarol and isochromazonarol, new chroma-
nols from the brown seaweed Dictyopteris undulata (zonariodes). Experientia
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5. (a) Barrero, A. F.; Alvarez-Manzaneda, E. J.; Chahboun, R. Enantiospecific
synthesis of wiedendiol-B from (2)-sclareol and (þ)-cis-albienol. Tetrahedron
Lett. 1997, 38, 8101–8104; (b) Barrero, A. F.; Alvarez-Manzaneda, E. J.;
Chahboun, R. Synthesis of wiedendiol-A and wiedendiol-B from labdane diter-
penes. Tetrahedron 1998, 54, 5635–5650; (c) Barrero, A. F.; Alvarez-
Manzaneda, E. J.; Mar Herrador, M.; Chahboun, R.; Galera, P. Synthesis of
antitumoral activities of marine ent-chromazonarol and related compounds.
Bioorg. Med. Lett. 1999, 9, 2325–2328; (d) Welch, S. C.; Paskasa Rao, A. S. C.
Stereoselective total synthesis of (+)-zonarol and (+)-isozonarol. Tetrahedron
Lett. 1977, 505–508; (e) Welch, S. C.; Paskasa Rao, A. S. C. Stereoselective
total syntheses of the fungitoxic hydroquinones (+)-zonarol and (+)-isozonarol.
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absolute configuration of zonarol, a fungitoxic hydroquinone from the brown
seaweed Dictyopteris zonarioides. Bull. Soc. Chim. Belg. 1986, 95, 771–781;
(g) Akita, H.; Nozawa, M.; Shimizu, H. Synthesis of decalin type chiral
synthons based on enzymatic functionalization and their application to the
synthesis of (2)-ambrox and (þ)-zonarol. Tetrahedron: Asymmetry 1998, 1,
¨
1789–1799; (h) Schroder, J.; Magg, C.; Seifert, K. Total synthesis of the marine
sesquiterpene hydroquinones zonarol and isozonarol and the sesquiterpene
quinones zonarone and isozonarone. Tetrahedron Lett. 2000, 41, 5469–5473.
6. (a) Villamizar, J.; Orcajo, A. L.; Fuentes, J.; Tropper, E.; Alonso, R. Highly
efficient synthesis of optically active sesquiterpene hydroquinone (þ)-zonarol