Polyamines
Polyamines are organic compounds characterized by multiple amino groups (-NH2) attached to an aliphatic carbon chain. The most common polyamine is spermidine, spermine, and their derivatives. Polyamines are found in all living cells and play essential roles in various biological processes, including DNA stabilization, RNA transcription and translation, protein synthesis, cell proliferation, and signaling pathways. They are involved in maintaining cellular homeostasis and are crucial for cell growth, differentiation, and survival. Polyamines also play roles in regulating ion channels and membrane permeability and have been implicated in the immune response and neurological functions. Their levels are tightly regulated within cells, and dysregulation of polyamine metabolism is associated with various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
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