882499-87-8 Usage
General Description
"Methyl 2-amino-5-bromo-4-pyridinecarboxylate" is a chemical compound with the molecular formula C7H7BrN2O2. It is a derivative of pyridine and contains a methyl group, amino group, and carboxylate group. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It has potential applications in the field of medicinal chemistry due to its structural properties and the presence of functional groups that make it suitable for further chemical modifications. Additionally, it has been studied for its potential biological activities and is of interest to researchers in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 882499-87-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,2,4,9 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 882499-87:
(8*8)+(7*8)+(6*2)+(5*4)+(4*9)+(3*9)+(2*8)+(1*7)=238
238 % 10 = 8
So 882499-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BrN2O2/c1-12-7(11)4-2-6(9)10-3-5(4)8/h2-3H,1H3,(H2,9,10)
882499-87-8Relevant articles and documents
THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS
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Paragraph 0538, (2020/12/11)
Disclosed herein are certain thiadiazolyl derivatives Formula (I): that inhibit DNA Polymerase Theta (Polθ) activity, in particular inhibit Polθ activity by inhibiting ATP dependent helicase domain activity of Polθ. Also, disclosed are pharmaceutical compositions comprising such compounds and methods of treating and/or preventing diseases treatable by inhibition of Polθ such as cancer, including homologous recombination (HR) deficient cancers.
Bisaryl-sulfonamides
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Page/Page column 29, (2008/06/13)
Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARγ or PPARδ. In particular, the compounds of the invention modulate the function of PPARγ or PPARδ. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis.