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1-(3-methoxy-4-nitrophenyl)piperidin-4-one is a chemical compound with the molecular formula C13H15N3O4. It is a piperidin-4-one derivative featuring a 3-methoxy-4-nitrophenyl group attached to the piperidine ring. 1-(3-methoxy-4-nitrophenyl)piperidin-4-one is recognized for its unique structure, which makes it a valuable component in medicinal chemistry and organic synthesis. Due to its potential as a building block in the synthesis of pharmaceuticals and other organic compounds, it has shown promise as an intermediate in the development of new drugs for various therapeutic applications. However, it is important to handle this compound with care and caution due to potential hazards associated with its use.

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  • 761440-64-6 Structure
  • Basic information

    1. Product Name: 1-(3-Methoxy-4-nitrophenyl)piperidin-4-one
    2. Synonyms: 1-(3-Methoxy-4-nitrophenyl)piperidin-4-one
    3. CAS NO:761440-64-6
    4. Molecular Formula: C12H14N2O4
    5. Molecular Weight: 250.25056
    6. EINECS: 1592732-453-0
    7. Product Categories: N/A
    8. Mol File: 761440-64-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(3-Methoxy-4-nitrophenyl)piperidin-4-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(3-Methoxy-4-nitrophenyl)piperidin-4-one(761440-64-6)
    11. EPA Substance Registry System: 1-(3-Methoxy-4-nitrophenyl)piperidin-4-one(761440-64-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 761440-64-6(Hazardous Substances Data)

761440-64-6 Usage

Uses

Used in Pharmaceutical Industry:
1-(3-methoxy-4-nitrophenyl)piperidin-4-one is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs for a range of therapeutic applications. Its unique structure allows it to be a key intermediate in the creation of various medicinal compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(3-methoxy-4-nitrophenyl)piperidin-4-one serves as a valuable component for creating a variety of organic compounds. Its versatility in chemical reactions makes it an essential part of many synthesis processes.

Check Digit Verification of cas no

The CAS Registry Mumber 761440-64-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,1,4,4 and 0 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 761440-64:
(8*7)+(7*6)+(6*1)+(5*4)+(4*4)+(3*0)+(2*6)+(1*4)=156
156 % 10 = 6
So 761440-64-6 is a valid CAS Registry Number.

761440-64-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(3-methoxy-4-nitrophenyl)piperidin-4-one

1.2 Other means of identification

Product number -
Other names methoxynitrophenyltetrahydropyridinone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:761440-64-6 SDS

761440-64-6Relevant articles and documents

Synthesis method of Brigatinib intermediate

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Paragraph 0034-0038; 0044-0051, (2021/06/26)

The invention discloses a synthesis method of a Brigatinib intermediate. The Brigatinib intermediate is 2-methoxy-4-(4-(4-methyl piperazine-1-yl) piperidine-1-yl) aniline (I). The synthesis method comprises the following steps: taking 5-fluoro-2-nitroanis

Substituted diaminopyrimidine compound

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Paragraph 0229-0234, (2019/07/04)

The present invention provides a substituted diaminopyrimidine compound represented by a formula (I), or a pharmaceutically acceptable salt, a crystal form, a prodrug, a metabolite, a hydrate, a solvate, a stereoisomer or an isotope derivative thereof, as well as a pharmaceutical composition and uses thereof. The compound provided by the invention can be used for treating ALK-mediated related diseases, such as non-small cell lung cancer, breast cancer, neural tumor, esophageal cancer, soft tissue cancer, lymphoma and leukemia.

Preparation method and crystal form of deuterated diphenyl amino pyrimidine compound

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Paragraph 0340-0344, (2019/04/27)

The present invention discloses a preparation method and a crystal form of a compound shown in the formula (A) and also discloses a pharmaceutical composition comprising the crystal form of the compound shown in the formula (A) and a method for treating A

DEUTERIUM-MODIFIED BRIGATINIB DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND USE THEREOF

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, (2018/10/15)

The present invention relates to the field of pharmaceutical chemistry, and relates to a deuterium-modified Brigatinib derivative, preparation method thereof, pharmaceutical composition containing the same and the uses of the deuterium-modified Brigatinib derivative and the pharmaceutical composition thereof in preparing a medicament for treating the disease mediated by anaplastic lymphoma kinase. The deuterium-modified Brigatinib derivative of the present invention has an excellent inhibitory activity on anaplastic lymphoma kinase and has better pharmacodynamic or pharmacokinetic properties relative to Brigatinib.

2,4-dibasic miazines compound

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, (2017/08/29)

The invention belongs to the field of medical chemistry, relates to a 2,4-dibasic miazines compound and specifically relates to a compound shown as formula (I) or a pharmaceutically acceptable salt thereof, a drug compound thereof and an application thereof in treating EGFR or/and ALK mediated diseases.

Diaminopyrimidine compound and composition containing same

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Paragraph 0112-0119, (2017/06/02)

The invention provides a diaminopyrimidine compound and a composition containing the same and discloses the diaminopyrimidine compound shown as in a formula (I) and a drug combination containing the compound or salt thereof acceptable in crystal form and

METHOD FOR PRODUCING DI(ARYLAMINO)ARYL COMPOUND, AND SYNTHETIC INTERMEDIATE THEREFOR

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Paragraph 0040, (2014/01/07)

Provided is a method for producing a di(arylamino)aryl compound that has superior inhibitory activity against the kinase activities of EML4-ALK fusion protein and mutant EGFR protein and is useful as an active ingredient in pharmaceutical compositions for cancer treatment. The production method includes no purification step using silica gel column chromatography or no step possibly producing a mutagenic mesylate ester as a by-product, greatly improves overall yield, and is high yield and low cost and suitable for the industrial production of pharmaceutical products. Also provided is a synthetic intermediate that is useful in the production method.

CHEMICAL COMPOUNDS

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, (2012/02/06)

The present invention relates to compounds of Formula (I) and/or Formula (Ia): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit ALK kinase activity, and thus may be used for the tr

THIAZOLE SULFONAMIDE AND OXAZOLE SULFONAMIDE KINASE INHIBITORS

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Page/Page column 144, (2010/10/03)

The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents

COMPOUNDS AND THERAPEUTIC USES THEREOF

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Page/Page column 130-131, (2010/11/03)

The invention relates to compounds, pharmaceutical compositions, and uses thereof, including therapeutic uses thereof, such as methods useful for treating cancer.

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