76045-71-1

Basic information

• Product Name: 3-AMINO-5-HYDROXYBENZOIC ACID
• Synonyms: 3-AMINO-5-HYDROXYBENZOIC ACID;Benzoic acid, 3-amino-5-hydroxy- (9CI);Benzoic acid, 3-amino-5-hydroxy-;5-AMINO-3-HYDROXYBENZOIC ACID;3-Hydroxy-5-aminobenzoic acid;3-amino-5-hydrobenzoic acid
• CAS NO: 76045-71-1
• Molecular Formula: C₇H₇NO₃
• Molecular Weight: 153.14
• Product Categories: CARBOXYLICACID
• Mol File: 76045-71-1.mol

Chemical Properties

• Melting Point: 242 °C
• Boiling Point: 453.4 °C at 760 mmHg
• Flash Point: 228 °C
• Appearance: /
• Density: 1.491 g/cm³
• Vapor Pressure: 5.2E-09mmHg at 25°C
• Refractive Index: 1.691
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.33±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-5-HYDROXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-5-HYDROXYBENZOIC ACID(76045-71-1)
• EPA Substance Registry System: 3-AMINO-5-HYDROXYBENZOIC ACID(76045-71-1)

Safety Data

• Hazardous Substances Data: 76045-71-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-5-hydroxybenzoic acid is used as a key intermediate in the synthesis of Meta-azacyclic Amino Benzoic Acid derivatives. These derivatives act as pan integrin antagonists, which are crucial in the treatment of various diseases by inhibiting the integrin-mediated cellular processes.
In the preparation of Meta-azacyclic Amino Benzoic Acid derivatives, 3-Amino-5-hydroxybenzoic acid serves as a building block for developing new drugs with potential therapeutic applications. Its unique structure allows for the creation of compounds that can target specific integrin receptors, making it a valuable asset in the development of novel pharmaceuticals.

InChI:InChI=1/C7H7NO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,8H2,(H,10,11)

Upstream product

• 78238-14-9 3-hydroxy-5-nitrobenzoic acid 
• 14206-69-0 3-amino-5-hydroxybenzoic acid hydrochloride 
• 141726-22-9 5-deoxy-5-amino-3-dehydroshikimic acid 
• 3615-55-2 D-ribose 5-phosphate 
• 138-08-9 phosphoenolpyruvic acid 
• 2702-58-1 methyl 3,5-dinitrobenzoate 
• 78238-13-8 3-methoxy-5-nitrobenzoic acid methyl ester 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 618-84-8 3-amino-5-nitro-benzoic acid 
• 99-34-3 3,5-dinitrobenzoic acid 
• 65-85-0 benzoic acid 
• 78238-12-7 3-methoxy-5-nitrobenzoic acid 

Downstream Products

• 216481-95-7 3-(2-Chloro-acetoxy)-5-(2-chloro-acetylamino)-benzoic acid 
• 726190-34-7 N-benzoyl-N'-(5-hydroxy-3-carboxyphenyl)thiourea 
• 717138-32-4 3-hydroxy-5-[[(methylamino)thioxomethyl]amino]benzoic acid 
• 240431-47-4 N-(5-hydroxy-3-carboxyphenyl)thiourea 
• 240431-50-9 N-(5-hydroxy-3-carboxyphenyl)-S-methylisothiourea 
• 406682-45-9 3-hydroxy-5-(1,4,5,6-tetrahydropyrimidin-2-ylamino)benzoic acid 
• 240431-49-6 3-hydroxy-5-[(5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino]benzoic acid 
• 779325-29-0 N-methyl-N'-(5-hydroxy-3-carboxyphenyl)-S-methyl-isothiourea 
• 726190-58-5 C₂₂H₂₃Cl₂N₅O₇C₂H₄ 
• 243135-77-5 (3R)-3-(3,5-dichloro-2-hydroxyphenyl)-3-[(N-{3-hydroxy-5-[(5-hydroxy-1,4,5,6-tetrahydropyrimidinyl)amino]benzoyl}glycyl)amino]propanoic acid 
• 951308-32-0 C₂₂H₂₃ClBrN₅O₆C₂H₄ 
• 726190-91-6 C₂₂H₂₃N₅O₇ClBrC₂H₄ 

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