60472-54-0

Basic information

• Product Name: Pyrrolidine, 1-[(4-ethenylphenyl)methyl]-
• CAS NO: 60472-54-0
• Molecular Formula: C13H17N
• Molecular Weight: 187.285
• Mol File: 60472-54-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Pyrrolidine, 1-[(4-ethenylphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 1-[(4-ethenylphenyl)methyl]-(60472-54-0)
• EPA Substance Registry System: Pyrrolidine, 1-[(4-ethenylphenyl)methyl]-(60472-54-0)

Safety Data

• Hazardous Substances Data: 60472-54-0(Hazardous Substances Data)

Usage

General Description

Pyrrolidine, 1-[(4-ethenylphenyl)methyl]- is a chemical compound with the molecular formula C15H19N. It is a derivative of pyrrolidine, a heterocyclic compound containing a five-membered ring with one nitrogen atom. The chemical structure of 1-[(4-ethenylphenyl)methyl]-pyrrolidine includes a pyrrolidine ring substituted with a phenyl group that contains a vinyl (ethenyl) group. Pyrrolidine, 1-[(4-ethenylphenyl)methyl]- is commonly used as a building block in organic synthesis and is employed in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Its versatile reactivity and structural properties make it a valuable tool in the chemical industry for creating various applications and products.

Upstream product

• 123-75-1 pyrrolidine 
• 1592-20-7 4-Vinylbenzyl chloride 
• 1075-49-6 4-ethenylbenzoic acid 

Downstream Products

• 1572176-76-1 1,1-bis(4-vinylbenzyl)pyrrolidin-1-ium bromide 
• 1572176-75-0 1-benzyl-1-(4-vinylbenzyl)pyrrolidinium bromide 
• 1572176-72-7 1-benzyl-1-(4-vinylbenzyl)pyrrolidinium bis[(trifluoromethyl)sulfonyl]imide 

Relevant articles and documents

Direct Catalytic Reductive N-Alkylation of Amines with Carboxylic Acids: Chemoselective Enamine Formation and further Functionalizations

Direct reductive N-alkylation of secondary amines with carboxylic acids using molybdenum hexacarbonyl (5 mol %) as catalyst and diethoxymethylsilane as reducing agent generate enamines in a straightforward fashion in high yields. The formed enamines are without the need for isolation or purification further reacted with trimethylsilyl cyanide in the same reaction flask to yield α-amino nitriles in good yields. In the optimized reaction conditions equimolar amounts of carboxylic acid and amine are reacted under neat conditions, and a catalytic amount of trifluoroethanol (0.1 mol %) is added along with TMSCN for the cyanation step. The reductive N-alkylation reaction is demonstrated to be highly chemoselective, tolerating a multitude of different functional groups present in the starting carboxylic acids and amines. The reaction is scalable and the generated α-amino nitriles are converted to other useful compounds, e.g., α-amino acids or amino-tetrazoles. In addition, the intermediate enamines are further transformed into triazolines, sulfonylformamidines, pyrimidinediones, and TMS-propargylamines, respectively, in high yields under mild reaction conditions. Benzoic acids react with secondary amines under similar conditions to give tertiary amines in high yields, and using this methodology, the biologically active compound Piribedil was isolated in 80% yield in a direct one-pot reaction setup.

Functionalized monomers for synthesis of rubbery polymers

This invention discloses a process for synthesizing an amine functionalized monomer that comprises (1) reacting a secondary amine with a 2,3-dihalopropene to produce a vinyl halide containing secondary amine having a structural formula selected from the g

Process for synthesizing functionalized styrene monomer

This invention discloses a rubbery polymer which is comprised of repeat units that are derived from (1) at least one conjugated diolefin monomer, and (2) at least one functionalized monomer having of the structural formula: wherein R represents an alkyl g