292150-20-0

Basic information

• Product Name: FMOC-alpha-glutaMine
• Synonyms: FMOC-alpha-glutaMine;(4R)-5-Amino-4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-5-oxopentanoic acid;Fmoc-D-glutamic acid α-amide≥ 99% (HPLC);Fmoc-D-Igln-OH;N-Fmoc-D-isoglutamine;(9H-Fluoren-9-yl)MethOxy]Carbonyl D-isoGln-OH;Fmoc-D-iso-Gln
• CAS NO: 292150-20-0
• Molecular Formula: C₂₀H₂₀N₂O₅
• Molecular Weight: 368.3832
• Mol File: 292150-20-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 687.715°C at 760 mmHg
• Flash Point: 369.717°C
• Appearance: /
• Density: 1.332g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.617
• Storage Temp.: 2-8°C
• CAS DataBase Reference: FMOC-alpha-glutaMine(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-alpha-glutaMine(292150-20-0)
• EPA Substance Registry System: FMOC-alpha-glutaMine(292150-20-0)

Safety Data

• Hazardous Substances Data: 292150-20-0(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

InChI:InChI=1/C20H20N2O5/c21-19(25)17(9-10-18(23)24)22-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H2,21,25)(H,22,26)(H,23,24)

Upstream product

• 104091-09-0 N-Fmoc-D-glutamic acid 
• 6893-26-1 D-Glutamic acid 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 1286246-26-1 C₂₀H₁₇NO₅ 
• 18800-76-5 Boc-D-Glu(OBzl)-OSu 
• 55297-72-8 (R)-5-amino-4-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid 
• 35793-73-8 N-(tert-butyloxycarbonyl)-γ-benzyl-D-glutamic acid 
• 2578-33-8 D-glutamic acid-5-benzyl ester 
• 18800-73-2 benzyl (R)-5-amino-4-((tert-butoxycarbonyl)amino)-5-oxopentanoate 
• 19522-40-8 D-α-glutamine 
• 63648-73-7 N-benzyloxycarbonyl-D-glutamic acid 
• 19522-39-5 (R)-5-amino-4-(((benzyloxy)carbonyl)amino)-5-oxopentanoic acid 

Downstream Products

• 1340480-93-4 Nα-[4-chlorocinnamoyl-L-alanyl-D-isoglutaminyl]-L-lysine 

Relevant articles and documents

CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE

The present invention discloses chemical synthesis, anti-tumor and anti-metastatic effects of a dual functional conjugate as showed by formula I. In detail, paclitaxel or docetaxol is linked with muramyl dipeptide derivative to form a conjugate, thus dual anti-tumor and anti-metastatic effects are achieved by combination of chemotherapy and immunotherapy. The present invention also discloses that paclitaxel or docetaxol and muramyl dipeptide derivative conjugate is synthesized by combination of solid-phase and solution-phase synthesis, and said conjugate can be used in manufacture of anti-tumor medicaments as proved by reliable bioassays.

A novel immunostimulator, N2-[α-O-Benzyl-N-(acetylmuramyl) -L-alanyl-D-isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-L-lysine, and its adjuvancy on the hepatitis B surface antigen

N2-[α-O-Benzyl-N-(acetylmuramyl)-L-alanyl-D-isoglutaminyl] -N6-trans-(m-nitrocinnamoyl)-L-lysine (muramyl dipeptide C, or MDP-C) has been synthesized as a novel, nonspecific immunomodulator. The present study shows that MDP-C induces