134486-00-3 Usage
Description
FMOC-3-IODO-L-TYROSINE, also known as N-(9-fluorenylmethoxycarbonyl)-3-iodo-L-tyrosine, is a synthetic amino acid derivative with a unique chemical structure. It is characterized by its white to off-white powder form and is widely utilized in various applications due to its specific properties.
Uses
Used in Pharmaceutical Industry:
FMOC-3-IODO-L-TYROSINE is used as a reagent for the synthesis of antitumor compounds, such as rubiyunnanin B dityrosine core, through Suzuki coupling. This application is significant because it contributes to the development of novel and effective anti-cancer drugs, potentially improving the treatment options for patients suffering from various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 134486-00-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,4,8 and 6 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 134486-00:
(8*1)+(7*3)+(6*4)+(5*4)+(4*8)+(3*6)+(2*0)+(1*0)=123
123 % 10 = 3
So 134486-00-3 is a valid CAS Registry Number.
134486-00-3Relevant articles and documents
Control of the iodination reaction on activated aromatic residues in peptides
Espuna, Gemma,Arsequell, Gemma,Valencia, Gregorio,Barluenga, Jose,Perez, Marta,Gonzalez, Jose M.
, p. 1307 - 1308 (2000)
By using a slight molar excess of the IPy2BF4 reagent in an acid containing medium, activated aromatic residues on Tyr derivatives and peptides selectively react yielding, as major products, the monoiododerivatives; this level of reaction control cannot be achieved by other iodinating methods.
SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE
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Page/Page column 24-25, (2008/06/13)
Provided are therapeutic and diagnostic somatostatin analogs including radiotherapeutic and radiodiagnostic reagents, and methods of making and use thereof.
