- Antifungal composition and method employing pyridinium compounds
-
Compounds containing a cation of formula Ia STR1 and a pharmaceutically acceptable anion are anti-fungal agents. In formula Ia and Ib R1 is alkyl of at least 3 carbon atoms or aralkyl; R2 and R5 are hydrogen, lower alkyl, lower alkoxy, halogen or nitro; R6 and R7, when separate, are lower alkyl or aryl(lower)alkyl or, when joined together, are --(CH2)2 --A--(CH2)2 -- (where A is --(CH2)n --, O, S or NR8 where n is O, 1 or 2 and R8 is lower alkyl) or a mono- or di-(lower alkyl) substitution product thereof.
- -
-
-