SYNTHESIS OF 5-(5-R-2-FURYL)THIAZOLE DERIVATIVES BY THE REACTION OF 2-(5-R-FURFURYL)THIURONIUM SALTS WITH ACETIC ANHYDRIDE
2-Acetamide-4-methyl-5-(5-R-2-furyl)thiazoles were obtained by the reaction of 2-(5-R-furfuryl)thiuronium salts with acetic anhydride.The reaction intermediates - 2-(5-R-furfuryl)-1,3-diacetylthioureas - were isolated and characterized.
Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines
A series of novel selenourea derivatives and corresponding thiourea analogs were synthesized and tested against a panel of six human cancer cell lines: melanoma (1205Lu), lung carcinoma (A549), prostatic carcinoma (DU145), colorectal carcinoma (HCT116), p
Alcolea, Verónica,Plano, Daniel,Karelia, Deepkamal N.,Palop, Juan Antonio,Amin, Shantu,Sanmartín, Carmen,Sharma, Arun K.
p. 134 - 144
(2016/03/01)
Synthesis and antimicrobial and nitric oxide synthase inhibitory activities of novel isothiourea derivatives
The reaction of substituted benzylhalides, or of halomethyl derivatives of thiophene or furane, with thiourea or its derivatives yielded the respective isothioureas as hydrohalide salts. The products (a total of 17, including 16 novel compounds) were test