Synthesis and Chemistry of Some Thieno-1,2,3-triazin-4(3H)-ones
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Huddleston, Patrick R.,Barker, John M.,Adamczewska, Yolante Z.,Wood, Michael L.,Holmes, David
p. 548 - 575
(2007/10/02)
The Fragmentation of 5- and 3-Substituted Thiophene-2-carboxamides Under Electron Impact
The 70 eV electron impact mass spectra of twelve 5- and 3-substituted thiophene-2-carboxamides are discussed with the aid of exact mass measurements and labelling experiments.All mass spectra exhibit pronounced molecular ions.Some isomeric 5- and 3-substituted title compounds can be differentiated by mass spectrometry.The fragmentation is influenced by a strong 'ortho-effect' which activates the NH3 elimination.In the other cases the most important fragmentation is NH2. loss, followed by CO elimination.