- A concise stereospecific synthesis of repinotan (BAYx3702)
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A concise synthesis of the 2-[aminomethyl]chroman derivative BAYx3702 (3), a potent 5-hydroxytryptamine (5-HT1A) antagonist is described. Utilization of a Mitsunobu reaction of phenol (11) with the non-racemic allylic alcohol (12) and consequen
- Gross, Jonathan L.
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- Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
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Compounds of the formula useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disord
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