- Concise total synthesis of AB5046A and AB5046B
-
Two naturally occurring rare 5-oxo β-triketones, AB5046A and AB5046B, were efficiently synthesized in five linear steps with overall yields of 36% and 28%, respectively. The synthetic strategy highlighted the readily preparation of the key intermediate, 3
- Kong, Lu-Yao,Cui, Qing,Jin, Zhong,Xu, Xiao-Hua
-
p. 1705 - 1707
(2018/04/10)
-
- Synthesis of ω-Acetyl-α-methylenpolyene Carboxylic Esters
-
The α-methylenpolyene carboxylic acids 1 and 2 are highly active against Gram-positive bacteria.If this activity arises from an interference with the cell membranes, then an abrupt change in biological properties is to be expected with growing chain length of simple model compounds.To make these tests possible, we describe here the synthesis of a series of homologue esters of type 40.Their synthesis was achieved by Wittig reactions of polyene α,ω-dialdehydes 6 with acetylmethylentriphenylphosphoran 5a and the protected carboxymethylmethylen triphenylphosphonium salt 8.
- Laatsch, Hartmut,Pudleiner, Alke
-
p. 663 - 677
(2007/10/02)
-
- Compounds with Urotropine Structure, LX. - Orthooxalic and Orthocarbonic Acid Derivatives with Adamantane Structure
-
Methyl trimethoxyacetate (1) and cis-1,3,5-cyclohexanetriol (2) easily react to give methyl 2,4,10-trioxaadamantane-3-carboxylate (3).Based on 3, further derivates of 2,4,10-trioxaadamantane are prepared.By degradation reactions, 3-bromo- and 3-amino-2,4,
- Stetter, Hermann,Hunds, Artur
-
p. 1577 - 1590
(2007/10/02)
-