- CYCLOHEXAPEPTIDES AS SELECTIVE SOMATOSTATIN SST5 RECEPTOR AGONISTS
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The disclosures herein relate to novel compounds of formula (1) : (1) and salts thereof, wherein W, X, Y, Z, m, n, q, R1, R2, R3, R4, R5 and R6 are defined herein, and their use in treating
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Page/Page column 35
(2020/05/19)
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- NOVEL PROCESS FOR THE PREPARATION OF PASIREOTIDE
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The present invention relates to a novel process for the preparation of Pasireotide of formula 11 [Cyclo [Phe-{4-(OCO-NH-CH2-CH2-NH2)) Pro}-Phg-DTrp-Lys-Tyr(Bzl)]]. The invention also relates to a novel intermediate compound of formula 8 and process thereof which is used for preparation of compound of formula 11.
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Page/Page column 24
(2017/01/09)
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- PROCESS FOR PEPTIDE SYNTHESIS OF PEPTIDES CONTAINING A 4-HYDROXY-PROLINE SUBSTRUCTURE
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The present invention relates to processes for preparing peptides and to intermediates involved in such processes, e.g. a process for preparing a compound of formula (VIII) wherein R12 and R13 are as defined herein.
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- A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential
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A rational drug design approach, capitalizing on structure-activity relationships and involving transposition of functional groups from somatotropin release inhibitory factor (SRIF) into a reduced size cyclohexapeptide template, has led to the discovery o
- Lewis, Ian,Bauer, Wilfried,Albert, Rainer,Chandramouli, Nagarajan,Pless, Janos,Weckbecker, Gisbert,Bruns, Christian
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p. 2334 - 2344
(2007/10/03)
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