- Stereocontrol in Nucleophilic Substitution Reactions at Silicon: The Role of Permutation in Generating Silicon-Centered Chirality
-
Intramolecular isomerization in pentacoordinate compounds can play an essential role for the adjustment of defined stereochemical information. Here, we present a conclusive mechanism of a stereocontrolled reaction on chiral dimethoxysilanes that opens new aspects in understanding the origin of creating silicon-centered chirality during a nucleophilic substitution process. By combining experimental, structural, and quantum chemical methods, we were able to disclose an interconversion process, based on consecutive Berry-type motions, as the most plausible mechanism for describing the stereochemical outcome in suchlike substitution reactions.
- Bauer, Jonathan O.,Strohmann, Carsten
-
-
Read Online
- METHOD FOR PRODUCING ORGANOSILICON COMPOUND HAVING CYCLIC ALKYL GROUP
-
PROBLEM TO BE SOLVED: To provide a method for producing an organosilicon compound that can efficiently produce an organosilicon compound, particularly an organic silicon compound having a cyclic alkyl group. SOLUTION: A method according to the present inv
- -
-
Paragraph 0022; 0025; 0028; 0029; 0030; 0031; 0034
(2019/01/06)
-
- Process for preparing low-chloride or chloride-free alkoxysilanes
-
A process for preparing an alkoxysilane with an acidic chloride content of less than 10 ppm by weight, comprising: reacting a chlorosilane with an alcohol in a water-free and solvent-free phase to form a product mixture containing alkoxysilane and residual acidic chloride, with removal of resultant hydrogen chloride from the product mixture, then adding liquid or gaseous ammonia, in an amount corresponding to a stoichiometric excess, based on the content of acidic chloride, to form an ammonia-containing product mixture, treating the ammonia-containing product mixture at a temperature between 10 and 50 DEG C., wherein the ammonia and acidic chloride undergo neutralization, to form a crude product, and optionally, then separating off a salt formed in the course of neutralization, from the crude product, and recovering the alkoxysilane by distilling the crude product.
- -
-
-
- A method for the preparation of a cycloalkyl silane compound
-
Cycloalkyl silane compound such as cyclohexyl methyl di-chlorosilane can be efficiently prepared by the photochemically induced hydrosilylation reaction. For example, an equimolar mix-ture of cyclohexene and methyl dichlorosilane and admixture of a catalytic amount of a platinum compound, e.g., chloroplatinic acid, is irradiated at a temperature up to 70 °C with ultraviolet light so that the hydrosilylation reaction takes place and proceeds almost to completeness without deactivation of the platinum catalyst to give the desired product in a yield of 90% or even higher.
- -
-
-