- Efficient Amination of Activated and Non-Activated C(sp3)?H Bonds with a Simple Iron–Phenanthroline Catalyst
-
A readily available catalyst consisting of iron dichloride in combination with 1,10-phenanthroline catalyzes the ring-closing C?H amination of N-benzoyloxyurea to form imidazolidin-2-ones in high yields. The C?H amination reaction is very general and applicable to benzylic, allylic, propargylic, and completely non-activated aliphatic C(sp3)?H bonds, and it also works for C(sp2)?H bonds. The surprisingly simple method can be performed under open flask conditions.
- Jarrige, Lucie,Zhou, Zijun,Hemming, Marcel,Meggers, Eric
-
supporting information
p. 6314 - 6319
(2021/02/01)
-
- Enantioselective Strecker and Allylation Reactions with Aldimines Catalyzed by Chiral Oxazaborolidinium Ions
-
Chiral oxazaborolidinium ion (COBI)-catalyzed enantioselective nucleophilic addition reactions of aldimines using tributyltin cyanide and allyltributylstannane have been developed. Various α-aminonitriles and homoallylic amines were synthesized in high yi
- Kang, Ki-Tae,Park, Sang Hyun,Ryu, Do Hyun
-
p. 6679 - 6683
(2019/09/12)
-
- Photoreactive fused aziridinylpiperazines on the background of 4-substituted chalcones and their benzimidazolic analogs
-
The reaction of bromo-substituted chalcones with various diamino-compounds leads to the fused heterocyclic products, aziridinylpiperazines, exhibiting photoreactivity in the crystalline state. Crystals of 4-nitrosubstituted compounds of this family change their color from yellowish to deep violet-blue, 4-cyanosubstituted ones – from yellowish to pink at UV irradiation. Discussion on the mechanism of this phototransformation is still in progress, however, several facts points to the free radial nature of the photogenerated colored semi-products stabilized only by crystalline state of the irradiated samples. Formation of a mixture of positional isomers at interaction of bromo-chalcones with asymmetric diamines of aliphatic/alicyclic or aromatic series at synthesis of the title compounds is of significant interest as well.
- Kotlyar, Volodymyr M.,Kolomoitsev, Oleksii O.,Nikolaievskyi, Dmytro V.,Pedan, Polina I.,Chumak, Andrii Yu,Orlov, Valery D.,Shishkina, Svitlana V.,Doroshenko, Andrey O.
-
p. 741 - 746
(2019/01/10)
-
- A practical synthesis of 1,2-nitroamines by Michael addition of N-nucleophiles to nitroalkenes
-
A practical method for the synthesis of-nitroamines by Michael addition of azide to nitroalkene has been developed. This reaction proceeds in high yields under very mild conditions (phase-transfer catalysis) and is found to be general; good yields are obtained with both aryl and alkyl derivatives as well as with 1,1-di-substituted ones. Georg Thieme Verlag Stuttgart - New York.
- Robiette, Raphael,Tran, Trieu-Van,Cordi, Alex,Tinant, Bernard,Marchand-Brynaert, Jacqueline
-
experimental part
p. 3138 - 3142
(2010/11/03)
-
- Asymmetric catalysis of carbon-carbon bond forming reactions using amino acid-derived C1-symmetrical salen ligands
-
Four amino acids (alanine, valine, phenylalanine and phenylglycine) have been converted into C1-symmetrical salen ligands and complexed to titanium, vanadium, copper and cobalt. The resulting complexes have been used as asymmetric catalysts for asymmetric cyanohydrin synthesis, asymmetric Strecker reactions, asymmetric synthesis of α-methyl amino acids and asymmetric Darzens condensations. Satisfactory levels of asymmetric induction were obtained from reactions in which the (salen)metal complex acts as a chiral Lewis acid, but low levels of asymmetric induction were obtained from reactions carried out under solid-liquid phase-transfer conditions.
- Belokon, Yuri N.,Hunt, Jamie,North, Michael
-
experimental part
p. 2804 - 2815
(2009/06/28)
-
- A new and facile route for the synthesis of chiral 1,2-diamines and 2,3-diamino acids
-
The synthesis of chiral diamines and diamino acids has been achieved from the corresponding N-arylsulfonyl aziridines through reaction with a chiral isocyanate and subsequent hydrolysis of 2-imidazolidinones. The method appears to be general and of wide applicability.
- Nadir, Upender K.,Krishna, R. Vijaya,Singh, Anamika
-
p. 479 - 482
(2007/10/03)
-
- The first catalytic asymmetric nitro-Mannich-type reaction promoted by a new heterobimetallic complex
-
The best ratio is 1:1:3 for the components Yb, K, and binaphthol in the new heterobimetallic complex, which efficiently catalyzes an asymmetric nitro-Mannich-type reaction. The desired nitro-Mannich products 2 are obtained with up to 91% ee starting from
- Yamada, Ken-Ichi,Harwood, Simon J.,Groeger, Harald,Shibasaki, Masakatsu
-
p. 3504 - 3506
(2007/10/03)
-
- SYNTHESIS OF 1,2-AMINOAZIDES. CONVERSION TO UNSYMMETRICAL VICINAL DIAMINES BY CATALYTIC HYDROGENATION OR REDUCTIVE ALKYLATION WITH DICHLOROBORANES.
-
1,2-aminoazides are easily prepared from 1,2-amino alcohols.Catalytic hydrogenation in the presence of palladium on charcoal or reductive alkylation with dichloroboranes afford with good yields unsymmetrically substituted vicinal diamines.
- Benalil, Aziza,Carboni, Bertrand,Vaultier, Michel
-
p. 8177 - 8194
(2007/10/02)
-
- Imidazo(2,1-b)thiazole derivatives, compositions containing same, and method of treating helminthiasis
-
Imidazo[2,1-b]thiazole derivatives are provided having the structure STR1 wherein R1 is hydrogen, lower alkyl or carboxy, and R2 is hydrogen, lower alkyl or phenyl. In addition, a method is provided for treating or inhibiting helmint
- -
-
-