Synthesis of Fluoro and Trifluoromethyl Derivatives of 2-Phenylquinolin-4-ol
A tert-butoxide base-mediated cyclization of fluoro- and trifluoromethyl-substituted Schiff bases 12-19 produces 4-tert-butoxyquinolines 23-30 which are hydrolyzed to quinolin-4-ols 31-38.
Janda, Lubomir,Nguyen, Johnny,Patterson, Steven E.,Strekowski, Lucjan
p. 1753 - 1756
(2007/10/02)
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