Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesis
Chemical inducers of dimerization (CIDs) are employed in a wide range of biological applications to control protein localization, modulate protein-protein interactions and improve drug lifetimes. These bifunctional chemical probes are assembled from two s
Marinec, Paul S.,Evans, Christopher G.,Gibbons, Garrett S.,Tarnowski, Malloree A.,Overbeek, Daniel L.,Gestwicki, Jason E.
experimental part
p. 5763 - 5768
(2009/12/09)
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