One-step synthesis of 2,4,5-trisubstituted pyrimidines
A simple and straightforward methodology towards the synthesis of 2,4,5-trisubstituted pyrimidines has been developed by one-step reaction of isoflavones with thiourea or guanidine. Ten 2-mercapto-4,5-diphenylpyrimidines and eight 2-amino-4,5-diphenylpyri