- METHOD FOR THE SYNTHESIS OF 4-ALKOXY-, 4-HYDROXY- AND 4-ARYLOXY-SUBSTITUTED TETRAHYDRO-FURO[3,4-B]FURAN-2(3H)-ONE COMPOUNDS
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The present invention relates to a method for the synthesis of enantiomerically and diastereomerically enriched 4-alkoxy-, 4-hydroxy- or 4-aryloxy- substituted tetrahydro-furo[3,4-b]furan-2(3H)-ones by aldol coupling of a suitable hydroxyl-protected hydro
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Page/Page column 21-22
(2009/04/25)
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- HEPATITIS C VIRUS INHIBITORS
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The present invention relates to new compounds useful for the treatment or prevention of hepatitis C, process for preparing them, and a composition for the treatment or prevention of hepatitis C comprising the compounds as an active ingredient.
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- Synthesis and Antiviral Activity of 9-Alkoxypurines. 2. 9-(2,3-Dihydroxypropoxy)-, 9-(3,4-Dihydroxybutoxy)-, and 9-(1,4-Dihydroxybut-2-oxy)purines
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Reaction of alkenoxyamines (3, 5) or (R,S)-, (R)-, and (S)-hydroxy-protected derivatives of hydroxyalkoxyamines (20a,b, 37a-c) with 4,6-dichloro-2,5-diformamidopyrimidine (4) and cyclization of the resultant 6-- and 6-(alkoxyamino)pyrimid
- Bailey, Stuart,Harnden, Michael R.,Jarvest, Richard L.,Parkin, Ann,Boyd, Malcolm R.
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